СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Preparation of suppository base

Preparation of suppository base

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / MAKING SUPPOSITORIES IN PRODUCTION / Preparation of suppository base

Preparation of suppository base

The stage of preparation of the suppository base begins with the sizing of its components. In the first stainless steel reactor with a steam jacket melt paraffin, in the second reactor melt hydrofat by supplying steam into the steam jacket. The heated hydrofat is transferred to the reactor with pre-melted paraffin by means of a pump. The mixture is heated to a temperature of 60-70 ° C and cocoa butter is added. In order to avoid changes in the modification of cocoa butter, heating should not exceed 70 ° C and be prolonged. After complete melting of the base it is stirred for 40 min with a stirrer. The melting point and the time of complete deformation are determined in the finished base.

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Information updated : 28 / 02 / 2026
In stock
Manufacturer : 1 year for Preparation of suppository base

Model: Suppository base

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Our service and customer service

The preparation of the suppository mass is carried out in a reactor, where the ready base is fed with compressed air and drug substances are added. As an example, the LT series reactor-mixer manufactured by the Italian company ZUMA s.r.l. is used. Mixers of this series are designed for the preparation of suppository mass, creams, ointments, etc. and are available in four sizes with the volume of the working tank 30, 60, 140 and 250 liters. The working tank of the reactor is a polished stainless steel tank with a water jacket for heating and melting of the mixture. The tank can be rotated by 90° for easy draining and washing. The agitator blades of the reactor are equipped with scraper blades. All working parts of the apparatus are made of stainless steel. The mixer reactor is equipped with safety guards and is manufactured according to international standard.

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Technical specifications

If the melting temperature of the base is higher or lower than the specified one, then paraffin or hydrofat is introduced into the base heated to 60-70 ° C with thorough mixing. The base is filtered through a druk-filter using a brass mesh or belting, analyzed by melting temperature, solidification and time of full deformation and transferred to the apparatus department.
Druk filters are pressurized capacitive filters. Druk-filters are vertical vessels (usually with a jacket) with an elliptical bottom.
The vessel filter housing can be open or closed. The upper part of the housing is fed with the slurry to be separated. The filtrate is discharged from the lower part. During filtration, compressed gas is fed into the slurry-filled housing.

Additional information

The filter baffle is located on the false bottom. The resulting sludge is washed, dried and discharged by means of an agitator through a hatch located on the side of the housing or in the center of the false bottom. In some designs, the sludge is removed after lowering the false bottom by moving the filter cloth belt, which passes through the regeneration chamber at the end of the sludge discharge. Druk filters are known, the body of which can be rotated by 90-180° in the trunnions fixed on its cylindrical part. Druk filters are used to separate medium and well-filtered suspensions in medium and low-tonnage productions.

Order status tracking

Roman Tsibulsky +79853643808 now online

Gabriel
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 04/03/2026 08:13

Roman Tsibulsky
Gabriel, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 04/03/2026 08:15

Alexander
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 04/03/2026 08:23

Roman Tsibulsky
Hello Alexander, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 04/03/2026 08:27

Olivia
Horizontal granulator for organic fertilizers JU-80, the price is up to date ? Delivery time to Valletta? Urgent. 04/03/2026 08:33

Roman Tsibulsky
Olivia, Please read carefully the description of this model in our catalog. Prices are current. Timing 1-1.5 months. 04/03/2026 08:36

Zoe
How to contact you for shipment tracking ? Industrial vibrating screen VS-04. 04/03/2026 08:43

Roman Tsibulsky
Good afternoon, Zoe, My WhastApp is +79853643808, Manager Natalia +79153808881 during business hours and except weekends. 04/03/2026 08:45

Alexander
You have to pay for delivery to Belgrade over and above the delivery amount in the contract ? 04/03/2026 08:53

Roman Tsibulsky
Alexander, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 04/03/2026 08:56

Layla
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 04/03/2026 09:03

Roman Tsibulsky
Layla, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer in the morning. We will report back immediately. 04/03/2026 09:06

Mia
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 04/03/2026 09:13

Roman Tsibulsky
Hello Mia, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in Zagreb to 50 working ( not calendar) days. Action taken. 04/03/2026 09:17

Muhammad
Tell me the NJ-120 automatic capsule machine went ? 04/03/2026 09:23

Roman Tsibulsky
Muhammad, good afternoon. Yes, already as agreed you will receive it. Taking into account the heavy weight of the equipment, we ask you to take care of unloading by forklift in advance. The transportation company does not provide unloading. Only delivery to the address. 04/03/2026 09:25

Elijah
Remember me? There's a delivery in the Paris 04/03/2026 09:33

Roman Tsibulsky
Elijah, Hello! We remember all our customers. your blister honey filling machine model MN-82 will be closer to evening in Paris . 04/03/2026 09:34

Mia
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 04/03/2026 09:43

Roman Tsibulsky
Hello Mia, Our manager Natalia tomorrow by lunchtime will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Constance in 15 days. 04/03/2026 09:47