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Subsequent atmospheric freeze drying was carried out in a boiling layer of adsorbent particles with a size of 80 microns. The rehydration properties of the products were not inferior to those obtained by vacuum freeze drying. Obtaining pharmaceutical protein-containing powders by freeze drying at atmospheric pressure in fluidized bed apparatuses opens wide prospects and advantages of their application. The dry product has high dispersibility, porosity, fast and complete solubility, good bulkiness and is ready for use. At the same time, dry powder can act as a semi-product and be used to produce tablets, capsules and other solid dosage forms, since its characteristics allow for mixing, pressing, granulation operations. The finished product due to its minimal particle size can be used for injectable, nasal, transdermal administration, has instant solubility and delivery properties of active components. Thus, the methods of atmospheric freeze drying are focused on obtaining products with particle size of micro- and nanosize with predetermined molecular structure and predetermined properties.
Pharmaceutical Glossary
Technical specifications
To cool the air to the required temperature, there is an additional cartridge located just before the conical part, which is filled with dry ice. The cylindrical part of the apparatus ends with a filter designed to catch and prevent fine particles from being carried away by the air stream. The filter is shaken periodically. Air, previously passed through the cartridge with dry ice, is supplied through the inlet opening of the conical part of the apparatus at a speed that provides a stable hydrodynamic regime. At the chamber outlet, the air is sequentially supplied for purification, heating and drying.
Additional information
Atmospheric freeze drying under conditions of convective heat supply allows: to intensify the process of moisture removal ten times; to significantly reduce the time of its implementation, while obtaining products that are not only not inferior in preserving useful properties to those freeze-dried in vacuum, but also superior to them in some qualitative characteristics; to organize the process not only in periodic, but also in semi-continuous and continuous modes. Scientists have demonstrated the suitability of atmospheric freeze drying for the treatment of coarse materials. However, due to the significant particle size (more than 1 cm) the process duration was an order of magnitude higher in comparison with vacuum freeze drying. To reduce the process time, part of the moisture was preliminarily removed by osmotic dehydration.
Order status tracking
Good afternoon, please confirm that in the interval from 10:00-12:00 we will receive our shipment in Granada? Contact the transportation company. 02/09/2026 13:17
Hello Andrew ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Granada in a few days. Please expect it. 02/09/2026 13:19
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 02/09/2026 13:27
Hello Ella, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 02/09/2026 13:30
Good afternoon, please confirm that tomorrow until 16:30 we will receive our shipment in Mont St. Michel? Contact the transportation company. 02/09/2026 13:37
Hello Sofia ! Representatives of the transportation company on the delivery status of your shipment said that it will be in Mont St. Michel in a few days. Please expect it. 02/09/2026 13:40
HX-9 plastic tube filling and sealing machine bought a month ago, arrival status in Mariehamn. 02/09/2026 13:47
Hello Mia, Delivery status checked, as agreed is arriving at Mariehamn . The driver will call you beforehand. 02/09/2026 13:51
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 02/09/2026 13:57
Logan, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in Portland ? Contact Natalia, she will send the contract and invoice. 02/09/2026 14:00
LB-205 horizontal automatic wet alcohol wipes packaging machine delivery status ...thank you 02/09/2026 14:07
Hello Luna, it is too early to check the status of your order. In 30 days only the epat of production will be completed. 02/09/2026 14:10
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 02/09/2026 14:17
Samuel, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in St. Louis ? Contact Natalia, she will send the contract and invoice. 02/09/2026 14:20
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 02/09/2026 14:27
Hello Sofia, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 02/09/2026 14:27
We received our order (BG-150 film coating boiler) in the box there was no spraying nozzle !!! 02/09/2026 14:37
Hello Wyatt, we checked with the factory. Your nozzle was not received in time for the shipment of the main machine. We will now deliver it to you by DHL express mail. 02/09/2026 14:37
Run through the order. V-shaped mixer for powders VM-50 and Mechanical tablet press PP-28 are waiting. 02/09/2026 14:47
Aiden, Checking delivery status. The shipment is already in Valletta warehouse. Please arrange for pickup. 02/09/2026 14:48
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- PERISTALTIC PUMPS DISPENSERS
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- PERISTALTIC PUMPS DISPENSERS
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
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