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Subsequent atmospheric freeze drying was carried out in a boiling layer of adsorbent particles with a size of 80 microns. The rehydration properties of the products were not inferior to those obtained by vacuum freeze drying. Obtaining pharmaceutical protein-containing powders by freeze drying at atmospheric pressure in fluidized bed apparatuses opens wide prospects and advantages of their application. The dry product has high dispersibility, porosity, fast and complete solubility, good bulkiness and is ready for use. At the same time, dry powder can act as a semi-product and be used to produce tablets, capsules and other solid dosage forms, since its characteristics allow for mixing, pressing, granulation operations. The finished product due to its minimal particle size can be used for injectable, nasal, transdermal administration, has instant solubility and delivery properties of active components. Thus, the methods of atmospheric freeze drying are focused on obtaining products with particle size of micro- and nanosize with predetermined molecular structure and predetermined properties.
Pharmaceutical Glossary
Technical specifications
To cool the air to the required temperature, there is an additional cartridge located just before the conical part, which is filled with dry ice. The cylindrical part of the apparatus ends with a filter designed to catch and prevent fine particles from being carried away by the air stream. The filter is shaken periodically. Air, previously passed through the cartridge with dry ice, is supplied through the inlet opening of the conical part of the apparatus at a speed that provides a stable hydrodynamic regime. At the chamber outlet, the air is sequentially supplied for purification, heating and drying.
Additional information
Atmospheric freeze drying under conditions of convective heat supply allows: to intensify the process of moisture removal ten times; to significantly reduce the time of its implementation, while obtaining products that are not only not inferior in preserving useful properties to those freeze-dried in vacuum, but also superior to them in some qualitative characteristics; to organize the process not only in periodic, but also in semi-continuous and continuous modes. Scientists have demonstrated the suitability of atmospheric freeze drying for the treatment of coarse materials. However, due to the significant particle size (more than 1 cm) the process duration was an order of magnitude higher in comparison with vacuum freeze drying. To reduce the process time, part of the moisture was preliminarily removed by osmotic dehydration.
Order status tracking
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 08/05/2024 13:00
Hello Liam, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 08/05/2024 13:01
Hello, I will quickly ask, what about BG-80 film coating boiler and HX-7 ultrasonic machine for sealing plastic tubes, contract No. 11 ???? 08/05/2024 13:10
Jackson, good afternoon! Your positions are produced by different factories, for HX-7 the factory reported that it is 90% ready, for BG-80 we are waiting for an answer as stipulated in the contract. We will report back immediately. 08/05/2024 13:12
Dear Roman, how are you doing? Our company bought more than a year ago a filling and capping machine for penicillin vials, model XL-10. We got financing this year and want the same machine. Will you give us a discount? 08/05/2024 13:20
Grayson, thank you. We're doing great. Of course we will give a discount to the regular customer. Delivery of equipment also in Phoenix ? Contact Natalia, she will send the contract and invoice. 08/05/2024 13:21
Granulator for wet granulation ZL-25 and Mixer V-shaped for powders VM-05 under contract No. 15 inform. 08/05/2024 13:30
Hello Aria, The shipment has arrived at the customs terminal, closer to evening is scheduled to be transferred to the transportation company. 08/05/2024 13:33
You have to pay for delivery to Rovinj over and above the delivery amount in the contract ? 08/05/2024 13:40
Lucy, The catalog shows the price with door delivery. The unloading of the equipment, upon receipt of the shipment, will be charged to you separately. 08/05/2024 13:41
The BB-152 liquid filling machine arrived from you today, remember us ? Where's the paperwork? 08/05/2024 13:50
{The original shipping documents will be delivered to Monte Carlo in the morning. Please send the signed copies to us. 08/05/2024 13:53
Horizontal granulator for organic fertilizers JU-80, the price is up to date ? Delivery time to Salzburg? Urgent. 08/05/2024 14:00
Violet, Please read carefully the description of this model in our catalog. Prices are current. Timing 1-1.5 months. 08/05/2024 14:04
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Sacramento. Please confirm the delivery time. 08/05/2024 14:10
Good afternoon Joseph, your shipment has left. Arrival time between 12:00-14:00. The driver will call you back later. Please organize prompt unloading. 08/05/2024 14:13
Contract #12, the deadline for delivery has already passed. Take action at last. Accelerate Tsibulsky R.G. 08/05/2024 14:20
Hello Aurora, we are on vacation on weekends and are not able to respond to messages. Raise the contract, delivery time of equipment to your warehouse in Vienna to 50 working ( not calendar) days. Action taken. 08/05/2024 14:20
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled in the morning to open the box and test. 08/05/2024 14:30
Scarlett, good afternoon. Great news, please send a photo and video report to WhatsApp +79853643808. 08/05/2024 14:31
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR COATING TABLETS
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- POWDER GRANULATION EQUIPMENT
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- AUTOMATIC CARTONING MACHINES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- PERISTALTIC PUMPS DISPENSERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- BOTTLE FILLING AND CAPPING EQUIPMENT
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- AUTOMATIC CARTONING MACHINES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES