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Subsequent atmospheric freeze drying was carried out in a boiling layer of adsorbent particles with a size of 80 microns. The rehydration properties of the products were not inferior to those obtained by vacuum freeze drying. Obtaining pharmaceutical protein-containing powders by freeze drying at atmospheric pressure in fluidized bed apparatuses opens wide prospects and advantages of their application. The dry product has high dispersibility, porosity, fast and complete solubility, good bulkiness and is ready for use. At the same time, dry powder can act as a semi-product and be used to produce tablets, capsules and other solid dosage forms, since its characteristics allow for mixing, pressing, granulation operations. The finished product due to its minimal particle size can be used for injectable, nasal, transdermal administration, has instant solubility and delivery properties of active components. Thus, the methods of atmospheric freeze drying are focused on obtaining products with particle size of micro- and nanosize with predetermined molecular structure and predetermined properties.
Pharmaceutical Glossary
Technical specifications
To cool the air to the required temperature, there is an additional cartridge located just before the conical part, which is filled with dry ice. The cylindrical part of the apparatus ends with a filter designed to catch and prevent fine particles from being carried away by the air stream. The filter is shaken periodically. Air, previously passed through the cartridge with dry ice, is supplied through the inlet opening of the conical part of the apparatus at a speed that provides a stable hydrodynamic regime. At the chamber outlet, the air is sequentially supplied for purification, heating and drying.
Additional information
Atmospheric freeze drying under conditions of convective heat supply allows: to intensify the process of moisture removal ten times; to significantly reduce the time of its implementation, while obtaining products that are not only not inferior in preserving useful properties to those freeze-dried in vacuum, but also superior to them in some qualitative characteristics; to organize the process not only in periodic, but also in semi-continuous and continuous modes. Scientists have demonstrated the suitability of atmospheric freeze drying for the treatment of coarse materials. However, due to the significant particle size (more than 1 cm) the process duration was an order of magnitude higher in comparison with vacuum freeze drying. To reduce the process time, part of the moisture was preliminarily removed by osmotic dehydration.
Order status tracking
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 04/07/2026 05:50
Hello Alexander, We are on time, tomorrow until 15:30 a driver will contact you about unloading. 04/07/2026 05:52
Good day, tell me need delivery in Stockton to the settlement in the distance of 20 km. Can you organize this? 04/07/2026 06:00
Hannah, Good afternoon, please send us an email to info@minipress.ru with the exact name of the equipment model, city, and your coordinates. We will calculate the delivery to you. 04/07/2026 06:03
Rotary tablet press RZK-25 I want to order with delivery to Berlin 04/07/2026 06:10
Good day, Alexander We have checked the information on your request, unfortunately the factory has stopped production of this model of equipment. Send to the mail a description of your task, or contact your manager. We will help in any case with the choice. 04/07/2026 06:13
Roman, our company bought VL-100 V-shaped powder mixer, but it is not enough for us, can we return it and exchange it for V-300 model? 04/07/2026 06:20
Ava, good afternoon. When we corresponded with you, I warned you that this is a model with a small load. Unfortunately we can not pick up the equipment. As an option, we will offer our customers with a discount. 04/07/2026 06:24
Can your technician come to Florence? We need technologist consultation and assistance. 04/07/2026 06:30
Elijah, We have already received your email. A technician between 12:00-14:00 will contact you. Don't worry. 04/07/2026 06:31
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 04/07/2026 06:40
Lila, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 04/07/2026 06:40
The MZ-10 expiration date and date handheld printer has still not been delivered. The driver did not answer and dropped calls yesterday. 04/07/2026 06:50
Hello Aiden, Transportation has advised that tomorrow until 16:30 driver will definitely deliver the box to your address. We apologize. 04/07/2026 06:54
We received our order (BG-150 film coating boiler) in the box there was no spraying nozzle !!! 04/07/2026 07:00
Hello Alexander, we checked with the factory. Your nozzle was not received in time for the shipment of the main machine. We will now deliver it to you by DHL express mail. 04/07/2026 07:00
Who to contact for shipment tracking ? NJ-40 automatic capsule machine in Jacksonville 04/07/2026 07:10
Hello Mia, The shipments are carried by a transportation company. Natalia coordinates this delivery. We will contact you when the shipment arrives to you. 04/07/2026 07:13
We have sent to info@minipress.ru photos of the damaged box with induction welding membrane machine FG-08. Please call back. 04/07/2026 07:20
Good day, David! Damage to the packaging is unfortunately a common practice in transportation. Please carefully unpack the shipment and send us a series of photos. We will take a look and take action. 04/07/2026 07:23
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- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
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- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
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- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
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- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
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- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
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- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
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