OINTMENT PRODUCTION LINE

Hydrophobic bases

8433

8518403

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VALVE-TYPE PLUNGER HOMOGENIZERS

9289

8526970

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Valve-type plunger homogenizers are designed for one-, two- and three-stage homogenization. This process takes place in a special valve system, which is the center of the entire homogenization process. When passing through the smallest openings in the valve under high pressure and constant monitoring, the product finds itself in conditions of high turbulence, which is the most effective mechanism for dividing into particles. The degree of fragmentation depends on the hydraulic conditions in the valve slot area. These conditions are mainly determined by the homogenization pressure, which determines the speed of movement of the ointment in the valve slot and its height, which determines the hydraulic radius of the flow. Valve-type homogenizers use multi-plunger high-pressure pumps with three, five and even seven plungers. When the plunger moves to the left, the ointment passes into the cylinder through the suction valve, and when the plunger moves to the right, it is pushed through the discharge valve into the chamber on which the pressure gauge is installed for pressure control. Next, the ointment is sent through the channel to the homogenizing head, in which the valve rises, pre...

SOFT DOSAGE FORMS, THEIR CLASSIFICATION AND PROPERTIES

9290

8526973

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The acquaintance of a person with soft medicinal forms occurs in the first days of life, when the caring hands of a mother apply baby cream to the delicate skin of a child. Then, throughout their lives, people use soft medicinal forms of medical appointment for the prevention and treatment of various diseases in dermatology with external therapy of skin lesions of various etiologies, gynecology, proctology, ophthalmology, as well as cosmetics to protect the skin from harmful effects and prolong its beauty and youth. In this chapter, classifications will be given, technologies for the production of soft dosage forms will be considered. Depending on the consistency, degree of viscosity and elasticity, the following can be attributed to soft dosage forms: Ointments; creams; Gels; Pastes; Liniments; suppositories; soft gelatin capsules (Capsulis); plasters (Emplastra). Ointments are a mild dosage form for topical use, intended for application to the skin, wounds or mucous membranes. They represent the most optimal dosage form in which it is possible to combine components that are different in chemical nature, aggregate states, prescriptions and biological activity. This is due to the...