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The most common combinations are the combination of a wet granulator-mixer with a spheronizer and an extruder with a spheronizer. Fluidized bed pelletizing. Pellets can be produced using a rotary insert in.a fluidized bed. The powder is mixed and moistened, the solvent or binder is fed tangentially. The powder layer is driven in a circular motion by the rotor insert. Process air, which is supplied through an adjustable gap at the edges of the rotor insert, drives the powder bed in a spiral motion. Agglomerates are formed which, due to the rotation of the rotor insert, are rolled into dense pellets with a regular spherical shape. The number of rotor revolutions has a direct influence on the density and size of the pellets. Drying of the wet pellets takes place either directly in the rotor during the drying phase at an elevated supply air temperature or in a fluidized bed dryer. Pellets are produced directly and very quickly from powder with the addition of a binder or solvent. The resulting pellets or pellets have a high density (comparable to the density of pellets produced in vertical pelletizers). If necessary, high-solid content shells are obtained by coating.
Pharmaceutical Glossary
Technical specifications
The particle size distribution of the resulting pellets is within a wide range of sizes. Pelletizing by rolling is the process of giving a spherical shape to extrudate after the extrusion process or to wet pellets after the wet granulation process. The spherical shaped pellets provide good stable friability and pellets with minimal mass variation are obtained. For example, in the study of granulates of calcium biphosphate, magnesium hydroxide and sulfadimezine prepared by wet granulation followed by rolling, it was found that their bulkiness increased by 40-100%. Rolling of wet pellets or extrudate is carried out on equipment called spheronizer. The principle of operation of a spheronizer is as follows: in the first stage, the material is compacted. With the help of a rotor-transfer granulator pellets are formed, which in the second stage are rolled in the spheronizer to a spherical shape and removed from the apparatus. In the presented GEA spheronizer, the plate is covered with smooth recesses. The plate is rotating and is tightly adhered to the walls of the apparatus. In this way, pellets with a good spherical shape are formed and a good particle size distribution is achieved.
Additional information
The granulate or extrudate is rolled to a spherical shape under the action of centrifugal and frictional forces. This design of the spheronizer solves the problem of material edge breakage and the appearance of unwanted small particles. Optimization of the process is achieved by selecting the rotation cycle time, plate speed, product loading and controlling the air flow around the periphery of the rotating plate. In the Glatt spheronizer, wet pelletized products or pre-formed extrudates are fed onto a rotating disk for pelletizing. The rotation of the disk, the flow of incoming product and a jet of air supplied through a slit in the side wall create an orderly product movement in a spiral path at the vessel wall. Due to intensive rolling, the surface of the particles is smoothed to form pellets. The dust particles generated in this process are captured again by the resulting pellets directly in the process. To increase the throughput capacity of the equipment in batch operation, several spheronizers are combined in a cascade. The cascade principle is also used to produce pellets with a laminated structure. The structure of the pellets is determined by the granulation process that takes place earlier in the process chain.
Order status tracking
Granulator for wet granulation ZL-25 and Mixer V-shaped for powders VM-05 under contract No. 15 inform. 11/07/2026 12:00
Hello Bella, The shipment has arrived at the customs terminal, as stipulated in the contract is scheduled to be transferred to the transportation company. 11/07/2026 12:00
Roman, can you tell me if my rotary tablet press RZJ-35 has been shipped yet? Don't send it yet, I will send to your factory in China drawings of new punches, different design. 11/07/2026 12:10
Good afternoon, Eleanor! We're pausing the shipment. Send drawings to the office mail. The terms of production of new punches 20 working days. 11/07/2026 12:12
Have you received payment from our company ? When can we expect delivery ? Please specify realistic terms. 11/07/2026 12:20
Good afternoon Gabriel, You paid a few hours ago. We told you that the delivery time is 30 to 45 days. tomorrow until 18: 30 we will get a reply from the manufacturer on the final time frame. 11/07/2026 12:23
Dear Roman. Deadline (time) I am waiting for your quotation for a machine for removing tablets and capsules from blister packs MB-10 with delivery. 11/07/2026 12:30
Hello Matthew, By the specified time we will send the offer to your e-mail. Now we are waiting for an answer from the transportation company on the delivery time to Oakland . 11/07/2026 12:32
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled in the interval from 10:00-12:00 to open the box and test. 11/07/2026 12:40
James, Good afternoon. Great news, please WhatsApp +79853643808 to send photo and video report. 11/07/2026 12:43
HX-6 Plastic Tube Filling and Sealing Machine in Salzburg? Price delivery terms and conditions 11/07/2026 12:50
Aiden, good afternoon, we have received your request by email. In 15 minutes we will send you our quotation for this model of equipment. 11/07/2026 12:53
Good day, I want after lunch to get FF-02 tablet and capsule filling machine in Helsinki? 11/07/2026 13:00
Good afternoon, Nova! We have contacted the transportation company, your shipment is arriving in Helsinki without delay. Please wait for a call from a representative of Business Lines. 11/07/2026 13:01
To what address to send you samples of bottles and caps to send them to the factory ? Regards Luna. 11/07/2026 13:10
Good day, Luna We received the same question on WhatsApp and replied there as well. Kindly provide the shipment number for tracking purposes. Thank you. 11/07/2026 13:12
Good afternoon, we received the PR-15 powder dispenser in plastic vials, scheduled between 16:00-18:00 to open the box and test. 11/07/2026 13:20
Aiden, Good afternoon. Great news, please WhatsApp +79853643808 to send photo and video report. 11/07/2026 13:21
PU-420 flow-pack packaging machine along with 500 kg packaging , delivery to Honolulu. Please confirm the delivery time. 11/07/2026 13:30
Good afternoon Mia, your shipment has left. Arrival time tomorrow until 16:30. The driver will call you back later. Please organize prompt unloading. 11/07/2026 13:31
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR COATING TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- BOTTLE FILLING AND CAPPING EQUIPMENT
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- PERISTALTIC PUMPS DISPENSERS
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR POLISHING AND DEDUSTING TABLETS AND CAPSULES
- EQUIPMENT FOR PACKAGING TABLETS AND CAPSULES IN PLASTIC BOTTLES
- EQUIPMENT FOR FILLING AND SEALING GLASS AMPOULES
- SPRAY DRYING EQUIPMENT FOR SUSPENSIONS
- EQUIPMENT FOR PACKING POWDERS INTO VIALS
- MACHINES FOR THE PRODUCTION OF SUPPOSITORIES
- EQUIPMENT FOR FILLING HARD GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR COATING TABLETS
- EQUIPMENT FOR FILLING CREAMS AND SEALING PLASTIC TUBES
- EQUIPMENT FOR WASHING AND STERILIZING BOTTLES
- EQUIPMENT FOR COUNTING AND PACKAGING TABLETS AND CAPSULES IN BOTTLES
- EQUIPMENT FOR THE PRODUCTION OF TABLETS
- HIGH-PRECISION DOSING MACHINES POWDER FILLING MACHINES
- EQUIPMENT FOR PRINTING LOGO ON TABLETS AND CAPSULES
- MACHINES FOR FORMING AND FILLING PLASTIC AMPOULES
- BOTTLE FILLING AND CAPPING EQUIPMENT
- AUTOMATIC EQUIPMENT FOR REMOVING TABLETS AND CAPSULES FROM BLISTERS
- EQUIPMENT FOR AUTOMATIC BOTTLE FEEDING FOR FILLING LINES
- EQUIPMENT FOR EFFICIENT MIXING OF POWDERS
- EQUIPMENT FOR HOMOGENIZING CREAMS AND OINTMENTS
- POWDER GRANULATION EQUIPMENT
- AUTOMATIC PHARMACEUTICAL CENTRIFUGES
- EQUIPMENT FOR SCREW FEEDING OF POWDERS
- EQUIPMENT FOR VACUUM TRANSPORTATION OF POWDERS
- EQUIPMENT FOR FILLING LIQUIDS IN PLASTIC AND METAL BARRELS
- EQUIPMENT FOR VACUUM PACKAGING IN PLASTIC BAGS
- AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- EQUIPMENT FOR PACKING TEA INTO TEA BAGS WITH THREAD AND LABEL
- EQUIPMENT FOR PACKAGING PRODUCTS IN A FLOW PACK
- EQUIPMENT FOR WRAPPING CARDBOARD BOXES WITH CELLOPHANE
- EQUIPMENT FOR PACKAGING BULK MATERIALS IN PLASTIC BAGS
- EQUIPMENT FOR INDUCTION SEALING OF ALU FOIL BOTTLES
- EQUIPMENT FOR PACKAGING TABLETS IN STRIPS AND TUBES
- EQUIPMENT FOR METAL DETECTOR IN GELATIN CAPSULES AND TABLETS
- EQUIPMENT FOR WEIGHT CONTROL AND SORTING OF CARDBOARD BOXES WITH MEDICINE
- EQUIPMENT FOR PACKAGING FOOD PRODUCTS IN DOY-PACK PACKAGES
- FLOW-PACK PACKAGING MACHINES
- EQUIPMENT FOR FILLING AND PACKAGING HERBAL TINCTURES
- AUTOMATIC EQUIPMENT FOR SELF-ADHESIVE LABELS ON PACKAGING
- EQUIPMENT FOR APPLYING THE EXPIRATION DATE AND BATCH NUMBER TO PRODUCTS
- EQUIPMENT FOR THE MANUFACTURE AND PACKAGING OF WET ALCOHOL WIPES
- SEMI-AUTOMATIC EQUIPMENT FOR FILLING GELATIN CAPSULES
- EQUIPMENT FOR LABORATORY TESTING OF MEDICINES
- SEMI-AUTOMATIC EQUIPMENT FOR BLISTER PACKAGING
- DESKTOP EQUIPMENT FOR LIQUID DOSING
- EQUIPMENT FOR POWDERING PHARMA RAW MATERIALS
- PERISTALTIC PUMPS DISPENSERS
- DESKTOP EQUIPMENT FOR MIXING POWDERS
- DESKTOP EQUIPMENT FOR HIGH-SPEED EMULSION PRODUCTION
- MANUAL EQUIPMENT FOR FILLING GELATIN CAPSULES WITH POWDER
- EQUIPMENT FOR MIXING LIQUIDS WITH MICROWAVE HEATING
- EQUIPMENT FOR AUTOMATIC DOSING OF CREAMS AND OINTMENTS
- EQUIPMENT FOR VIBRATING SIEVING OF POWDERS
- MACHINES PRINTING EXPIRATION DATE AND LOT NUMBER
- EQUIPMENT FOR THE PRODUCTION OF FISHING BOILIES
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