СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Force to push tablets out of the matrix

Force to push tablets out of the matrix

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СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / Force to push tablets out of the matrix

Force to push tablets out of the matrix

To push the pressed tablet out of the die, a force is required to overcome the friction and adhesion between the side of the tablet and the die wall. Based on the magnitude of the ejection force, additions of sliding (sliding or lubricating) agents are predicted. As an example, the results of determining the technological characteristics of rounded-shaped substances are presented. Powders with rounded particles with basic particle size more than 100 microns (Ranitidine g/hl, carbamazepine, phenazepam) have high (8-9 g/s) bulkiness, high volumetric density before and after compaction, but insignificant compressibility and small compaction coefficient.
Phenazepam has a slightly lower bulkiness value (8 g/s), probably because it contains more fines and does not contain particles larger than 250 microns, which are present in ranitidine and carbamazepine.

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Information updated : 11 / 01 / 2026
In stock
Manufacturer : 1 year for Force to push tablets out of the matrix

Model: Force to push tablets out of the matrix

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The image of the object surface topography is visually observed on the monitor screen and recorded on large-format photographic film. The principle of operation of the electron scanning microscope is as follows: a narrow beam of electrons with kinetic energy of the order of 1-25 kV falls on the sample under study. Electrons of the reflected beam (secondary electrons), released by atoms on the surface, form an image that is registered on the screen or microphotograph. In order to avoid sample damage or combustion, the sample is pre-coated with a conductive layer (usually a thin layer of gold) to prevent charging of the surface. The method of electron scanning microscopy allows to determine with high resolution the structure of the studied samples, shape and size of particles, pore size, pore size distribution, surface porosity and visualize pore geometry.

Pharmaceutical Glossary

Antifriction agents — A group of materials that have a low coefficient of friction, or materials that can reduce the coefficient of friction of other materials.

Technical specifications

This once again proves the fact that the finer the particles, the lower the friability.
The above-described technological characteristics of powdered drug substances are of paramount importance in the development of composition and technology of tablet forms, which should provide the necessary bioavailability and, accordingly, the effectiveness and safety of the drug.
Technological characteristics of powders are established quickly enough, methods of their determination are simple and do not cause difficulties, therefore these methods are now widely used in the pharmaceutical industry for mass control of all incoming drug substances.

Additional information

As a rule, pharmaceutical companies analyze the dispersibility of drug substances by such available methods as sieve analysis, microscopy, using a laser particle analyzer, etc. This allows already at the stage of selection of firms-suppliers of drug substances to exclude non-standard substances in the developed technological process and ensure high quality of domestic tablet preparations. The method of electron scanning microscopy can be used to determine such properties as surface, shape and size of particles. Stationary electron scanning microscope designed to study the topography (microgeometry) of the surface of a solid body by secondary electron emission.

Order status tracking

Roman Tsibulsky +79853643808 now online

Emily
LW-35 automatic PVC+cardboard blister packaging machine has been on the road for 30 days. What news ? 31/01/2026 07:28

Roman Tsibulsky
Hello Emily, We are on time, tomorrow until 18: 30 a driver will contact you about unloading. 31/01/2026 07:32

Isabella
Good afternoon, we have contracted you to deliver a GK-40 dry powder granulator to Luzern, do you deliver to the terminal or to the actual address? 31/01/2026 07:38

Roman Tsibulsky
Hello Isabella, we deliver all over USA including to Luzern . The price in the catalog includes any delivery our customer asks for. 31/01/2026 07:39

Michael
Excuse me, I have important information, please do not deliver my shipment, automatic filling and sealing machine for glass ampoules ALG-10 to Sigisoara, but immediately upon arrival send it to Riga. 31/01/2026 07:48

Roman Tsibulsky
Hello Michael, we will try to resolve this issue for you. 31/01/2026 07:51

Isabella
Dear Roman, good afternoon, vacuum powder conveyors QV-05 in quantity of 4 pieces, already on their way to Sarajevo ? 31/01/2026 07:58

Roman Tsibulsky
Good afternoon, Isabella! Our manager has sent a scan of the bill of lading to your email. The shipment is on its way. 31/01/2026 08:02

Logan
Hello, is it possible to buy your blistering machine for tablets and capsules MN-80 1 piece with delivery to Sacramento ( Europe) ? How much time for delivery ? 31/01/2026 08:08

Roman Tsibulsky
Logan, hello! We have many customers from your city. Delivery to this region is made by EMC. 31/01/2026 08:08

Ruby
When purchasing the RY-200 centrifugal type powder granulator, I asked for tests on our powder 31/01/2026 08:18

Roman Tsibulsky
Hello Ruby, Please send 2 kg of your raw material to the address given to you by Natalia. After the test, the engineer will inform you about the results. 31/01/2026 08:22

Elijah
Today we were promised delivery of a blister machine for MN-14 tablets and capsules, remember us ? No one's called us back. 31/01/2026 08:28

Roman Tsibulsky
Hello Elijah, Our manager Natalya tomorrow until 12:30 will dial the driver, also we ask you yourself to the transportation company. 31/01/2026 08:31

Carter
Good day , Electronic conveyor belt package weight detector DK-05 when will we receive in Brussels ? 31/01/2026 08:38

Roman Tsibulsky
Hello Carter, your shipment is in the customs warehouse, tomorrow until 14:30 your manager Natalia will contact you. 31/01/2026 08:39

William
Natalia tell me, automatic double-sided labeling machine ST-36 has left the factory, invoice #118. 31/01/2026 08:48

Roman Tsibulsky
Hello William, The equipment has been shipped from the transit warehouse and delivery is proceeding as planned. No delays are expected. 31/01/2026 08:50

Emilia
Roman, can you tell me if my rotary tablet press RZJ-35 has been shipped yet? Don't send it yet, I will send to your factory in China drawings of new punches, different design. 31/01/2026 08:58

Roman Tsibulsky
Good afternoon, Emilia! We're pausing the shipment. Send drawings to the office mail. The terms of production of new punches 20 working days. 31/01/2026 08:59