СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / GRANULATION PROCESS IN TABLET PRODUCTION / Binders for wet granulation

Binders for wet granulation

8331

7977017

Get new business partners

Check out our Instagram profile

Add the manager's contact to your WhatsApp

Watch us on our official TikTok account

Subscribe to our official YouTube channel

New business

There is a new industry actively developing in the US – CBD oil encapsulation. Capsules are used for treatment and prevention of diseases. Our company produces equipment for CBD oil encapsulation. WATCH 15 PROMO VIDEOS >>

EQUIPMENT CATALOG NOVELTIES :

СATALOGUE / PHARMACEUTICAL PRODUCTION TECHNOLOGIES / GRANULATION PROCESS IN TABLET PRODUCTION / Binders for wet granulation

Binders for wet granulation

There are some requirements for the granulating liquid, one of them is that the granulating liquid must not dissolve the active ingredient. Water, aqueous ethanol solution, acetone and methylene chloride can be used as granulating liquid. A wide range of substances are used as binders for wet granulation in modern pharmaceutical production, for example: starch (5-15 % g/g), starch derivatives, cellulose derivatives, which improve the plasticity of granules, as well as gelatin (1-3 % g/g) and PVP (3-10 % g/g). The most common and effective wet granulation binder in the modern pharmaceutical industry is a synthetic polymer such as Collidon (PVP), the various grades of which (Collidon 25, 30 and 90F) are widely available on the market.

Whatever your challenge, MINIPRESS is ready to take it on. We are more powerful than many competitors and our service is much more convenient. We provide customers with impressive terms and amazingly fast turnaround times. Our specialists use the most advanced technologies in the world to select various equipment. We have everything you need for modern production of any level. And even more.

Price: $ 0 HOW TO LOWER THE PRICE?

Download the quotation (PDF file)

Information updated: 09 / 04 / 2026
Available for
Production: 1 year на оборудование для влажной грануляции

Model: Wet granulation

Expert Services Index

Step-by-step assessment of your task by experts and a detailed discussion of solution options within 24 hours.
Company selection manufacturer and negotiations with selected provider.
Selection, optimal for the client, payment scheme and delivery time.
Assume responsibility and risks for delivery, insurance and customs cargo clearance in USA. Further transit to countries.
Receiving and checking equipmentbefore sending with a video report.
On arrival in USA delivery of equipment to your door.
Consultation from our specialist with 20 years of experience throughout the life of the equipment.
Export to any world countries. Air, sea and road transport with the necessary documents.
Equipment on lease with an advance payment of 10%. Convenient payment schedule. No limit. Approval for three documents: passport, lease agreement and extract. We cooperate with leasing companies.

If you did not find the equipment you need in our catalog, then call +79853643808 or make a request in the tab “Request a Call” and we will definitely offer you what you were looking for, or we will select similar equipment that will suit not only the technical characteristics, but also the price.
Guaranteed up to 15% discount on our services when subsequent purchase in the pharmaceutical equipment catalog.
Only quality equipment from proven suppliers with a long-term reputation.
Flexible payment system. Convenient payment acceptance for customers.

Equipment leasing with advance payment from 10%

Tablet coating machine BG-40

Vibrating dosing machine for bulk products DG-02

Horizontal automatic wet alcohol wipes packaging machine LB-205

Video review of the model

More videos of this model :

Our service and customer service

Plasdon polymers have excellent bonding ability, good film forming properties, surfactant properties and high solubility in water and many solvents used in pharmaceutical applications. Due to this combination of properties, these polymers are widely used in a number of pharmaceuticals. Plasdone polymers have long been used as binding agents in wet granulation. Plasdone®S-630 Copovidone is a synthetic 60:40 linear polymer of N-vinyl-2 pyrrolidone and vinyl acetate. With its unique properties, Plasdone S-630 is well suited as a tablet binder for direct pressing and dry granulation applications, as well as a wet granulation binder.

Pharmaceutical Glossary

Articles — A genre of journalism in which the author sets the task of analyzing social situations, processes, phenomena, primarily from the point of view of the regularities underlying them.

Technical specifications

The granules obtained with PVP are hard, easy to bulk, forming harder tablets with low brittleness. PVP polymer improves the solubility of the active ingredient by forming complexes. In addition, PVP acts as a crystallization inhibitor. The regularities presented below were identified by BASF’s fine chemistry department. They are discussed using Collidon as an example. Wet granulation using Collidon 25, Collidon 30 and Collidon 90F generally results in a harder granular material with better bulk properties than other binders – less abrasion and higher bond strength. The polymer content of the granulating fluid used can vary from Collidon 25 – 2-5%; Collidon 30 – 2-5%; Collidon 90F – 1-3%.

Additional information

Thus, BASF’s research showed that Collidon 90F produced the highest tablet hardness at the same pressing pressure. All binders were used in the amount of 3%. Based on the data presented, it can be concluded that the increased hardness and reduced brittleness of calcium phosphate tablets when Collidon 30 is used as a binder in the wet granulation process. In addition to Collidon, there are a large number of substances used as binders in the pharmaceutical industry. Let us consider two of them. PlasdonPPovidone is a series of synthetic water-soluble homopolymers of N-vinyl-2 pyrrolidone.

Order status tracking

Roman Tsibulsky +79853643808 now online

Aria
Vacuum lyophilic freeze dryer LG-30, can we get faster than the contract ? 20/04/2026 19:58

Roman Tsibulsky
Hello Aria, Shipments go through several time stages. Manufacturing, delivery from the factory to the warehouse in Beijing or Shanghai, waiting for batch collection, customs clearance and delivery. It's hard to predict. 20/04/2026 19:59

Alexander
Vacuum powder conveyor QV-01 quantity of 3 pieces, need discount and delivery to Fresno. 20/04/2026 20:08

Roman Tsibulsky
Good day Alexander, in our catalog all prices are given including delivery to the door of the customer. If you buy 3 pieces we will make a discount of 7%. Delivery to Fresno is included in the price. 20/04/2026 20:09

Layla
Hello Roman! Thank you for the service and quality of your products. We are very happy and satisfied with the purchase! 20/04/2026 20:18

Roman Tsibulsky
Hello Layla, Apparently you have tested your vacuum lyophilic dryer LZY-01. Its quality is above average, it will work. We are waiting for your new applications. 20/04/2026 20:20

Dylan
We received our order (BG-150 film coating boiler) in the box there was no spraying nozzle !!! 20/04/2026 20:28

Roman Tsibulsky
Hello Dylan, we checked with the factory. Your nozzle was not received in time for the shipment of the main machine. We will now deliver it to you by DHL express mail. 20/04/2026 20:31

Chloe
YR-90 dry and wet powder granulator YR-90 month has already passed. Hurry up the factory. 20/04/2026 20:38

Roman Tsibulsky
Chloe, good afternoon. The factory has shipped your equipment to our representative, now is forming a consolidated shipment for shipment to customs. We will keep you informed. 20/04/2026 20:40

Grace
Run through the order. V-shaped mixer for powders VM-50 and Mechanical tablet press PP-28 are waiting. 20/04/2026 20:48

Roman Tsibulsky
Grace, Checking delivery status. The shipment is already in Madrid warehouse. Please arrange for pickup. 20/04/2026 20:51

Chloe
Good afternoon! semi-automatic liquid filling machine in barrels DF-13 , a copy of the payment is sent to the post. Start the order to work. 20/04/2026 20:58

Roman Tsibulsky
Chloe, good afternoon! We have seen your payment, we receive SMS from the bank. Please send drawings of barrels and answers to our questions in correspondence. 20/04/2026 20:59

William
Good day, delivery time of semi-automatic drum filling machine DF-10 to Valencia, will the courier call us? 20/04/2026 21:08

Roman Tsibulsky
William, good afternoon. Natalia will contact you, the shipment has passed customs clearance at the border. 20/04/2026 21:10

Jackson
Natalia hello, what about the counter table tablets and capsules counter TC-10, account #121. 20/04/2026 21:18

Roman Tsibulsky
Hello Jackson, Our manager Natalia between 16:00-18:00 will call you on WhatsApp. I see the tracking status, on the carrier's website, the shipment will arrive to Lyme in 15 days. 20/04/2026 21:21

Henry
To what address to send you samples of bottles and caps to send them to the factory ? Regards Henry. 20/04/2026 21:28

Roman Tsibulsky
Good day, Henry We received the same question on WhatsApp and replied there as well. Kindly provide the shipment number for tracking purposes. Thank you. 20/04/2026 21:30