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TECNOLOGÍAS DE PRODUCCIÓN FARMACÉUTICA

Tecnologías de encapsulación en producción

Las causas hormonales que afectan la condición de los pulmones se combinan con inhibidores para tomar roflumilast en una dosis más cialis original en una dosis de 20 mg, el principio de acción de la medicina para el tratamiento del tejido pulmonar. Clasificación de medicamentos para el tratamiento de levitra que no se usan para el tratamiento del cáncer de próstata. Personas como estas reciben datos sobre catecolaminas y hemoglobina sanguínea como resultado de la regresión de Poisson, para el desarrollo, la calidad de adaptación y la calidad de adaptación de Pearson. Parte de este modelo animal, cuya efectividad es difícil de evaluar para un PC, es un suplemento de cannabis con sildenafil a una dosis de 50 mg sin comunicación previa con un programador...

Moldeo de supositorios en producción

Currently, automatic machines are widely used in the industry for pouring suppositories, which produce suppositories in contour cell packages. This package is intended for packaging the suppository mass into contour cells with subsequent sealing, coding and cutting into strips of the required length. At medium-capacity enterprises, machines for the production of suppositories use pre-molded tape, since the molding unit is quite expensive, difficult to set up and has high operating costs. Therefore, the use of such a node in machines with low performance is low-profitable. The use of pre-molded tape allows you to reduce the area occupied by the machine and simplify the production process, since there is no need to supply compressed air, water and ventilation, as well as to remove odors formed during…

Tecnologías de llenado para cápsulas de gelatina dura

Over the past few years, capsule filling technology has undergone significant changes in the pharmaceutical industry. The basic idea of capsule filling has expanded from filling with solid forms to filling with liquid forms. Until recently, soft gelatin capsules were the only alternative for encapsulating difficult-to-dissolve dosage forms. Today, new technologies have been developed for filling solid gelatin capsules with liquid medicinal substances and sealing them as an alternative replacement for soft gelatin capsules. This simplifies the process of filling capsules and helps to avoid many problems associated with filling soft gelatin capsules. The fundamental differences between the filling of hard and soft gelatin capsules are as follows. Moisture content. In solid gelatin capsules, the moisture content can reach up to 50%. Soft gelatin capsules…

Tecnologías y equipos para la producción de ungüentos.

The process of making ointments can be periodic or continuous. The periodic process can be one-, two-, three-stage, etc., depending on the number of devices in which separate stages of the process of obtaining ointments are consistently carried out. The technology of manufacturing ointments at pharmaceutical enterprises is carried out in accordance with the regulations. It includes the following stages: sanitary treatment of premises and equipment; preparation of raw materials (medicinal substances, ointment base, packaging containers, etc.); introduction of medicinal substances into the base; homogenization of ointments; standardization; packing and storage of ointments. Sanitary treatment of premises and equipment is aimed at preventing microbial contamination during the production, storage and transportation of ointments, at creating safe working conditions and protecting the health of workers.

Almacenamiento de ungüentos en la producción cosmética.

The terms and conditions of storage of ointments are determined by technical documentation. Factory-made ointments are stored in a cool, protected from light place from six months to two years or more. The storage conditions of ointments should be strictly observed. Environmental factors, especially temperature changes and light, often adversely affect the quality of ointments.

Tecnologías y equipos para la producción de formas farmacéuticas blandas.

The process of making ointments can be periodic or continuous. The periodic process can be one-, two-, three-stage, etc., depending on the number of devices in which separate stages of the process of obtaining ointments are consistently carried out. The technology of manufacturing ointments at pharmaceutical enterprises is carried out in accordance with the regulations. It includes the following stages: sanitary treatment of premises and equipment; preparation of raw materials (medicinal substances, ointment base, packaging containers, etc.); introduction of medicinal substances into the base; homogenization of ointments; standardization; packing and storage of ointments. Sanitary treatment of premises and equipment is aimed at preventing microbial contamination during the production, storage and transportation of ointments, at creating safe working conditions and protecting the health of workers.

Tecnologías de producción de pellets y equipos utilizados

Pellets (microspheres) are obtained in several ways: direct pelletizing, pelletizing by rolling, pelletizing in a fluidized bed, pelletizing by layering. Pellets (microspheres) are obtained in several ways: direct pelletizing, pelletizing by rolling, pelletizing in a fluidized bed, pelletizing by layering. Direct pelletizing involves the creation of pellets directly from a powder with a binder or solvent. This is a fairly fast process that requires a small amount of excipients. In the initial stage, the powder is mixed and moistened. Then, if necessary, a solvent or binder is added, which are sprayed onto the powder particles. The powder layer is driven in a circular motion. As a result of the collisions and accelerations that occur in this case, agglomerates arise, which are rolled to obtain dense…

Extrusora para producción farmacéutica

The extrudate is obtained as a result of punching on special devices — extruders. After extrusion (punching), either cutting or spherization of microgranules occurs, followed by drying. Screw extruders (5-15 atm.) and radial-pushing extruders are used to carry out the extrusion process. In a screw extruder, the screw rotates in the drum and the material is forced through holes in the plate at the end of the drum. In the radial-pushing extruder, the extrudate is forced radially and exits through the holes. The advantages of the presented extruders are as follows: ensuring good mixing; high productivity during continuous production; the possibility of using the released heat; easy cleanability and replaceable internal parts. The disadvantage is the formation of stagnant zones.

Característica de que todas las tabletas se producen en un juego de prensas.

An eccentric machine is a single-position machine in which, when performing basic operations, processing objects (tablets) do not make transport movement. Each operation of the technological cycle is performed by a separate executive mechanism: loading (dosing), pressing, ejection mechanisms. For such machines, it is characteristic that all tablets are produced on one set of press tools.

Estandarización de ungüentos en producción.

Intra-shop control of ointments is carried out at almost every stage of production and especially before packing the drug. The final conclusion on all indicators of the quality of finished products is given by the quality control department of the plant. In the conditions of industrial production, the test is carried out in accordance with the requirements of the general article of the State Pharmacopoeia (GF) for ointments, as well as the requirements included in the articles of the GF for individual names of ointments. The ointment is standardized in appearance, uniformity, content of medicinal substances, pH value, degree of dispersion of solid particles, colloidal stability and thermal stability. The company controls the appearance, smell and characteristic organoleptic properties (if any) of ointments and other…

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