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TECNOLOGÍAS DE PRODUCCIÓN FARMACÉUTICA

The term "coated coating" comes from the French word "dragee" and means "applying a sugar coating". A drained tablet consists of a core tablet containing a medicinal substance (substance) and a coating containing several excipients. The core tablet must be mechanically strong. Tablets to be drained should not have a flat shape to avoid sticking together. Let's consider one of the old methods of coating — sugar coating. Sugar coating is an effective way of applying large layers of coatings, primarily to mask the taste. This type of coating is used for temperature-sensitive and brittle solid dosage forms. The first stage of this technology is the spraying of a solution for spraying onto a particle (tablet, pellet). The air supplied to the device evaporates the liquid and dries the sugar layer. With intermittent supply of the solution, the particles remain in the process until the desired layer thickness is reached. The coating of particles is carried out evenly over the surface, while the mass of the layer varies from 0.5 to 2 mm. Currently, a large number of tablets are being drained, including: tablets of some hormonal medecines; some choleretic agents; synthetic medecines (glutami...