TECNOLOGÍAS DE PRODUCCIÓN FARMACÉUTICA

One of the problems of tablet production is obtaining good granulate fluidity in feeding devices (funnels, bunkers). The resulting granules or powders have a rough surface, which makes it difficult for them to pour out of the loading funnel into the matrix sockets. In addition, the granules can stick to the walls of the die and punch due to friction developed in the contact zones of the particles with the press tool of the tablet machine. To remove or reduce these undesirable phenomena, antifriction substances are used, represented by a group of sliding and lubricating substances. Sliding substances, adsorbed on the surface of particles (granules), eliminate or reduce roughness, increasing their fluidity (flowability). Particles having a spherical shape have the greatest sliding efficiency.