TECNOLOGÍAS DE PRODUCCIÓN FARMACÉUTICA

Problems encountered during coating application

8359

8501597

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Requisitos básicos para tabletas

8428

8502294

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Prensado directo de polvos en producción

8472

8502732

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Polimerización y policondensación

8513

8503139

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Peletización en la producción farmacéutica

8475

8502759

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Producción industrial de yesos

8433

8502341

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Peletización por capas

8475

8502761

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Máquinas rotativas de comprimidos

8490

8502912

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Rotary tablet machines (RTM), unlike eccentric ones, have a large number of matrices and punches. The matrices are mounted in a rotating matrix table. The pressure in the RTM increases gradually, which ensures a soft and uniform pressing of the tablets. rTMS have high productivity (up to 0.5 million tablets per hour). The technological cycle of tableting on RTM consists of a number of sequential operations: Filling the matrices with tableted material (volumetric dosing method). Actually pressing. Ejection. Dropping pills. The operations are performed sequentially in automatic mode. The upper and lower punches slide along the guides (caps) and pass between the pressing rollers, exerting simultaneous pressure on them. The pressure increases and decreases gradually, which leads to uniform and soft pressing of the tablet from above and below. Depending on the type, such machines can be equipped with one or two fixed loading funnels. An agitator can be installed in the loading funnels. The sequence of movement of one of the matrices consists of the following operations: Download operation. The lower punch 3 dropped into the precisely determined position. The upper punch 2 is in the up...

Requisitos básicos de las formas farmacéuticas blandas gmp

8433

8502344

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In the production of ointments, creams and other soft dosage forms, there is a particularly high risk of microbial and other contamination. Therefore, special measures are needed to prevent any contamination. Soft dosage forms have specific rheological properties and in most cases are heterogeneous dispersed systems. Therefore, in order to avoid heterogeneity of the product due to uneven distribution of components, formation of gas emulsions and destabilization of dispersed systems, special attention should be paid to the proper conduct of the technological process, the equipment used and the temperature conditions of product storage. Requirements for production facilities and equipment. The environment of the premises, taking into account all measures to protect production, should pose a minimal risk in terms of contamination of materials and products.

Cribado de polvo en producción

8488

8502894

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