{"id":67514,"date":"2024-01-16T12:22:20","date_gmt":"1970-01-01T00:00:00","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=67514"},"modified":"2024-01-16T12:22:20","modified_gmt":"1970-01-01T00:00:00","slug":"dragee-coatings-on-tablets-dragees-capsules-nuts-chewing-gums","status":"publish","type":"post","link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/medicine-manufacturing-from-experts\/dragee-coatings-on-tablets-dragees-capsules-nuts-chewing-gums\/","title":{"rendered":"DRAGEE COATINGS ON TABLETS, DRAGEES, CAPSULES, NUTS, CHEWING GUMS"},"content":{"rendered":"
The<\/span> term<\/span> \"coated<\/span> coating\"<\/span> comes<\/span> from<\/span> the<\/span> French<\/span> word<\/span> \"dragee\"<\/span> and<\/span> means<\/span> \"applying<\/span> a<\/span> sugar<\/span> coating\".<\/span>\n\nA<\/span> drained<\/span> tablet<\/span> consists<\/span> of<\/span> a<\/span> core<\/span> tablet<\/span> containing<\/span> a<\/span> medicinal<\/span> substance<\/span> (substance)<\/span> and<\/span> a<\/span> coating<\/span> containing<\/span> several<\/span> excipients.<\/span> The<\/span> core<\/span> tablet<\/span> must<\/span> be<\/span> mechanically<\/span> strong.<\/span> Tablets<\/span> to<\/span> be<\/span> drained<\/span> should<\/span> not<\/span> have<\/span> a<\/span> flat<\/span> shape<\/span> to<\/span> avoid<\/span> sticking<\/span> together.<\/span>\n\nLet's<\/span> consider<\/span> one<\/span> of<\/span> the<\/span> old<\/span> methods<\/span> of<\/span> coating<\/span> \u2014<\/span> sugar<\/span> coating.<\/span> Sugar<\/span> coating<\/span> is<\/span> an<\/span> effective<\/span> way<\/span> of<\/span> applying<\/span> large<\/span> layers<\/span> of<\/span> coatings,<\/span> primarily<\/span> to<\/span> mask<\/span> the<\/span> taste.<\/span> This<\/span> type<\/span> of<\/span> coating<\/span> is<\/span> used<\/span> for<\/span> temperature-sensitive<\/span> and<\/span> brittle<\/span> solid<\/span> dosage<\/span> forms.<\/span>\n\nThe<\/span> first<\/span> stage<\/span> of<\/span> this<\/span> technology<\/span> is<\/span> the<\/span> spraying<\/span> of<\/span> a<\/span> solution<\/span> for<\/span> spraying<\/span> onto<\/span> a<\/span> particle<\/span> (tablet,<\/span> pellet).<\/span> The<\/span> air<\/span> supplied<\/span> to<\/span> the<\/span> device<\/span> evaporates<\/span> the<\/span> liquid<\/span> and<\/span> dries<\/span> the<\/span> sugar<\/span> layer.<\/span> With<\/span> intermittent<\/span> supply<\/span> of<\/span> the<\/span> solution,<\/span> the<\/span> particles<\/span> remain<\/span> in<\/span> the<\/span> process<\/span> until<\/span> the<\/span> desired<\/span> layer<\/span> thickness<\/span> is<\/span> reached.<\/span> The<\/span> coating<\/span> of<\/span> particles<\/span> is<\/span> carried<\/span> out<\/span> evenly<\/span> over<\/span> the<\/span> surface,<\/span> while<\/span> the<\/span> mass<\/span> of<\/span> the<\/span> layer<\/span> varies<\/span> from<\/span> 0.5<\/span> to<\/span> 2<\/span> mm.<\/span> Currently,<\/span> a<\/span> large<\/span> number<\/span> of<\/span> tablets<\/span> are<\/span> being<\/span> drained,<\/span> including:<\/span> tablets<\/span> of<\/span> some<\/span> hormonal<\/span> medicine;<\/span> some<\/span> choleretic<\/span> agents;<\/span> synthetic<\/span> preparations<\/span> (glutamic<\/span> acid,<\/span> akrikhin,<\/span> diprozine,<\/span> methionine,<\/span> etc.);<\/span> a<\/span> number<\/span> of<\/span> extracts<\/span> (buckthorn,<\/span> krovohlebki,<\/span> krasavki,<\/span> etc.)<\/span>\n\nDraining<\/span> is<\/span> carried<\/span> out<\/span> in<\/span> draining<\/span> machine (obductors)<\/span> of<\/span> three<\/span> forms:<\/span> spherical,<\/span> ellipsoid<\/span> and<\/span> pear-shaped.<\/span> The<\/span> most<\/span> common<\/span> is<\/span> an<\/span> ellipsoid<\/span> shape.<\/span> Its<\/span> advantages<\/span> consist<\/span> in<\/span> the<\/span> possibility<\/span> of<\/span> greater<\/span> loading<\/span> of<\/span> tablets,<\/span> thereby<\/span> achieving<\/span> greater<\/span> productivity<\/span> during<\/span> this<\/span> process.<\/span> In<\/span> addition,<\/span> ellipsoidal<\/span> coating machine<\/span> create<\/span> optimal<\/span> rotational<\/span> movements<\/span> of<\/span> the<\/span> coated<\/span> tablets,<\/span> accelerating<\/span> and<\/span> improving<\/span> the<\/span> coating<\/span> conditions.<\/span>\n\nThe<\/span> coating machine<\/span> rotates<\/span> in<\/span> a<\/span> clockwise<\/span> direction<\/span> around<\/span> the<\/span> axis,<\/span> located<\/span> at<\/span> an<\/span> angle<\/span> (vertical<\/span> and<\/span> horizontal<\/span> mixing),<\/span> which<\/span> allows<\/span> you<\/span> to<\/span> achieve<\/span> good<\/span> mixing.<\/span> The<\/span> diameter<\/span> of<\/span> coating machine<\/span>,<\/span> most<\/span> often<\/span> made<\/span> of<\/span> copper,<\/span> ranges<\/span> from<\/span> 0.7<\/span> to<\/span> 1.5<\/span> m.<\/span> The<\/span> angle<\/span> of<\/span> inclination<\/span> of<\/span> the<\/span> coating machine<\/span> to<\/span> the<\/span> horizontal<\/span> is<\/span> 30\u00b0-45\u00b0,<\/span> the<\/span> optimal<\/span> loading<\/span> is<\/span> 25-30%<\/span> of<\/span> the<\/span> coating<\/span> volume.<\/span> The<\/span> optimal<\/span> rotation<\/span> speed<\/span> of<\/span> the<\/span> coating machine<\/span> is<\/span> 20-40<\/span> rpm,<\/span> the<\/span> number<\/span> of<\/span> revolutions<\/span> is<\/span> selected<\/span> depending<\/span> on<\/span> the<\/span> course<\/span> of<\/span> the<\/span> technological<\/span> process.<\/span>\n\nWhatever<\/span> task<\/span> you<\/span> have<\/span> in<\/span> front<\/span> of<\/span> you,<\/span> MINIPRESS<\/span> is<\/span> ready<\/span> to<\/span> take<\/span> it<\/span> up.<\/span> We<\/span> are<\/span> more<\/span> powerful<\/span> than<\/span> many<\/span> competitors<\/span> and<\/span> our<\/span> service<\/span> is<\/span> much<\/span> more<\/span> convenient.<\/span> We<\/span> provide<\/span> our<\/span> clients<\/span> with<\/span> impressive<\/span> conditions<\/span> and<\/span> execute<\/span> orders<\/span> amazingly<\/span> quickly.<\/span> Our<\/span> specialists<\/span> use<\/span> the<\/span> most<\/span> advanced<\/span> technologies<\/span> in<\/span> the<\/span> world<\/span> to<\/span> select<\/span> various<\/span> equipment.<\/span> We<\/span> have<\/span> everything<\/span> you<\/span> need<\/span> for<\/span> modern<\/span> production<\/span> at<\/span> any<\/span> level.<\/span> And<\/span> even<\/span> more.<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
The term “coated coating” comes from the French word “dragee” and means “applying a sugar coating”. A drained tablet consists of a core tablet containing a medicinal substance (substance) and a coating containing several excipients. The core tablet must be mechanically strong. Tablets to be drained should not have a flat shape to avoid sticking…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"two_page_speed":[]},"categories":[2299,3010],"tags":[2380,75,76,2381,2372,2376,2373,78,43,41,81,2377,2370,2379,63,95,2375,2371],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Author Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"MEDICINE MANUFACTURING FROM EXPERTS<\/a> TABLET PACKAGING<\/a>","rttpg_excerpt":"The term \"coated coating\" comes from the French word \"dragee\" and means \"applying a sugar coating\". A drained tablet consists of a core tablet containing a medicinal substance (substance) and a coating containing several excipients. The core tablet must be mechanically strong. Tablets to be drained should not have a flat shape to avoid sticking...","_links":{"self":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/67514"}],"collection":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/comments?post=67514"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/67514\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/media?parent=67514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/categories?post=67514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/tags?post=67514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}