{"id":59961,"date":"2024-01-16T15:24:10","date_gmt":"1970-01-01T00:00:00","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=59961"},"modified":"2024-01-16T15:24:10","modified_gmt":"1970-01-01T00:00:00","slug":"physicochemical-properties-of-powdered-medicine-substances","status":"publish","type":"post","link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/technologies-and-equipment-for-the-production-of-powders\/physicochemical-properties-of-powdered-medicine-substances\/","title":{"rendered":"Physicochemical properties of powdered medicine substances"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text]<\/span>\n\nThe<\/span> shape<\/span> and<\/span> size<\/span> of<\/span> the<\/span> particles.<\/span> Pharmaceutical<\/span> substances<\/span> are<\/span> polydisperse<\/span> powders,<\/span> have<\/span> a<\/span> complex<\/span> shape<\/span> and,<\/span> as<\/span> a<\/span> rule,<\/span> significant<\/span> roughness.<\/span> Powdered<\/span> medicinal<\/span> substances<\/span> (substances)<\/span> are<\/span> systems<\/span> having<\/span> particles<\/span> of<\/span> various<\/span> shapes<\/span> and<\/span> sizes.<\/span> In<\/span> many<\/span> medicinal<\/span> substances,<\/span> the<\/span> particles<\/span> are<\/span> anisodiametric<\/span> (asymmetric,<\/span> misaligned).<\/span> They<\/span> can<\/span> be<\/span> elongated<\/span> (sticks,<\/span> needles)<\/span> or<\/span> lamellar<\/span> (plates,<\/span> scales,<\/span> leaves).<\/span> A<\/span> smaller<\/span> part<\/span> of<\/span> powdery<\/span> substances<\/span> has<\/span> isodiametric<\/span> (symmetrical,<\/span> equiaxed)<\/span> particles<\/span> \u2014<\/span> these<\/span> are<\/span> spherical<\/span> formations.<\/span> For<\/span> example,<\/span> in<\/span> JSC<\/span> \"Chemical<\/span> and<\/span> Pharmaceutical<\/span> Combine<\/span> \"AKRIKHIN\",<\/span> studies<\/span> of<\/span> samples<\/span> of<\/span> substances<\/span> were<\/span> carried<\/span> out,<\/span> which<\/span> showed<\/span> that<\/span> all<\/span> the<\/span> variety<\/span> of<\/span> shapes<\/span> of<\/span> their<\/span> crystals<\/span> in<\/span> a<\/span> planar<\/span> projection<\/span> can<\/span> be<\/span> reduced<\/span> to<\/span> several<\/span> geometric<\/span> shapes,<\/span> such<\/span> as<\/span> spheres,<\/span> flat<\/span> plates<\/span> (having<\/span> practically<\/span> no<\/span> thickness),<\/span> volumetric<\/span> plates,<\/span> sticks,<\/span> needles<\/span> and<\/span> prisms.<\/span>\nIt<\/span> should<\/span> be<\/span> noted<\/span> that<\/span> some<\/span> powders<\/span> may<\/span> contain<\/span> crystals<\/span> of<\/span> different<\/span> shapes<\/span> and<\/span> their<\/span> fragments:<\/span> for<\/span> example,<\/span> the<\/span> substance<\/span> of<\/span> acyclovir,<\/span> along<\/span> with<\/span> lamellar<\/span> particles,<\/span> has<\/span> fractions<\/span> in<\/span> the<\/span> form<\/span> of<\/span> sticks<\/span> and<\/span> prisms,<\/span> and<\/span> the<\/span> nq-rosh<\/span> of<\/span> loratadine<\/span> contains<\/span> particles<\/span> in<\/span> the<\/span> form<\/span> of<\/span> sticks,<\/span> plates<\/span> and<\/span> polyhedra<\/span> of<\/span> rounded<\/span> shape.<\/span> All<\/span> the<\/span> powders<\/span> studied<\/span> were<\/span> divided<\/span> into<\/span> six<\/span> groups<\/span> according<\/span> to<\/span> the<\/span> shape<\/span> of<\/span> the<\/span> particles<\/span> of<\/span> the<\/span> main<\/span> fraction.<\/span> It<\/span> is<\/span> considered<\/span> that<\/span> the<\/span> dominant<\/span> fractions<\/span> have<\/span> the<\/span> greatest<\/span> influence<\/span> on<\/span> the<\/span> technological<\/span> properties<\/span> of<\/span> powders,<\/span> therefore,<\/span> strict<\/span> characterization<\/span> of<\/span> linear<\/span> dimensions<\/span> and<\/span> shape<\/span> is<\/span> necessary<\/span> for<\/span> these<\/span> fractions.<\/span>\n\n[\/vc_column_text][\/vc_column][\/vc_row]<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text] The shape and size of the particles. Pharmaceutical substances are polydisperse powders, have a complex shape and, as a rule, significant roughness. Powdered medicinal substances (substances) are systems having particles of various shapes and sizes. In many medicinal substances, the particles are anisodiametric (asymmetric, misaligned). They can be elongated (sticks, needles) or lamellar (plates,…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"two_page_speed":[]},"categories":[2243],"tags":[2380,2381,2372,2376,2373,263,2378,2374,73,43,2377,2370,40,2191,2379,67,119,2375,2371,2262,2257,66],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Author Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"TECHNOLOGIES AND EQUIPMENT FOR THE PRODUCTION OF POWDERS<\/a>","rttpg_excerpt":"[vc_row][vc_column][vc_column_text] The shape and size of the particles. Pharmaceutical substances are polydisperse powders, have a complex shape and, as a rule, significant roughness. Powdered medicinal substances (substances) are systems having particles of various shapes and sizes. In many medicinal substances, the particles are anisodiametric (asymmetric, misaligned). They can be elongated (sticks, needles) or lamellar (plates,...","_links":{"self":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/59961"}],"collection":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/comments?post=59961"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/59961\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/media?parent=59961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/categories?post=59961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/tags?post=59961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}