{"id":59004,"date":"2024-01-16T13:20:35","date_gmt":"1970-01-01T00:00:00","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=59004"},"modified":"2024-01-18T15:59:49","modified_gmt":"2024-01-18T12:59:49","slug":"basic-requirements-of-gmp-soft-dosage-forms","status":"publish","type":"post","link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/pharmaceutical-production-technologies\/basic-requirements-of-gmp-soft-dosage-forms\/","title":{"rendered":"Basic requirements of gmp soft dosage forms"},"content":{"rendered":"
In<\/span> the<\/span> production<\/span> of<\/span> ointments,<\/span> creams<\/span> and<\/span> other<\/span> soft<\/span> dosage<\/span> forms,<\/span> there<\/span> is<\/span> a<\/span> particularly<\/span> high<\/span> risk<\/span> of<\/span> microbial<\/span> and<\/span> other<\/span> contamination.<\/span> Therefore,<\/span> special<\/span> measures<\/span> are<\/span> needed<\/span> to<\/span> prevent<\/span> any<\/span> contamination.<\/span> Soft<\/span> dosage<\/span> forms<\/span> have<\/span> specific<\/span> rheological<\/span> properties<\/span> and<\/span> in<\/span> most<\/span> cases<\/span> are<\/span> heterogeneous<\/span> dispersed<\/span> systems.<\/span> Therefore,<\/span> in<\/span> order<\/span> to<\/span> avoid<\/span> heterogeneity<\/span> of<\/span> the<\/span> product<\/span> due<\/span> to<\/span> uneven<\/span> distribution<\/span> of<\/span> components,<\/span> formation<\/span> of<\/span> gas<\/span> emulsions<\/span> and<\/span> destabilization<\/span> of<\/span> dispersed<\/span> systems,<\/span> special<\/span> attention<\/span> should<\/span> be<\/span> paid<\/span> to<\/span> the<\/span> proper<\/span> conduct<\/span> of<\/span> the<\/span> technological<\/span> process,<\/span> the<\/span> equipment<\/span> used<\/span> and<\/span> the<\/span> temperature<\/span> conditions<\/span> of<\/span> product<\/span> storage.<\/span>\nRequirements<\/span> for<\/span> production<\/span> facilities<\/span> and<\/span> equipment.<\/span> The<\/span> environment<\/span> of<\/span> the<\/span> premises,<\/span> taking<\/span> into<\/span> account<\/span> all<\/span> measures<\/span> to<\/span> protect<\/span> production,<\/span> should<\/span> pose<\/span> a<\/span> minimal<\/span> risk<\/span> in<\/span> terms<\/span> of<\/span> contamination<\/span> of<\/span> materials<\/span> and<\/span> products.<\/span>\n<\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
In the production of ointments, creams and other soft dosage forms, there is a particularly high risk of microbial and other contamination. Therefore, special measures are needed to prevent any contamination. Soft dosage forms have specific rheological properties and in most cases are heterogeneous dispersed systems. Therefore, in order to avoid heterogeneity of the product…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"two_page_speed":[]},"categories":[3173,3201,2175,2213,2214],"tags":[2380,2381,2372,2376,2373,2197,2378,2374,156,193,2200,43,2218,2377,2370,2220,2191,2379,155,194,39,2375,2219,2216,2371,2217],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Author Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"ANTIBACTERIAL OINTMENT<\/a> BASE FOR THE PRODUCTION OF OINTMENTS<\/a> PHARMACEUTICAL PRODUCTION TECHNOLOGIES<\/a> TECHNOLOGY OF DOSAGE FORMS IN PRODUCTION<\/a> TECHNOLOGY OF SOFT DOSAGE FORMS<\/a>","rttpg_excerpt":"In the production of ointments, creams and other soft dosage forms, there is a particularly high risk of microbial and other contamination. Therefore, special measures are needed to prevent any contamination. Soft dosage forms have specific rheological properties and in most cases are heterogeneous dispersed systems. Therefore, in order to avoid heterogeneity of the product...","_links":{"self":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/59004"}],"collection":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/comments?post=59004"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/59004\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/media?parent=59004"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/categories?post=59004"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/tags?post=59004"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}