{"id":58222,"date":"2024-01-16T13:21:07","date_gmt":"1970-01-01T00:00:00","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=58222"},"modified":"2024-01-16T13:21:07","modified_gmt":"1970-01-01T00:00:00","slug":"film-coatings-for-modified-release-applications","status":"publish","type":"post","link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/pharmaceutical-production-technologies\/film-coatings-for-modified-release-applications\/","title":{"rendered":"Film coatings for modified-release applications"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text]<\/span>\n\nModified<\/span> release<\/span> film<\/span> coatings<\/span> can<\/span> be<\/span> applied<\/span> to<\/span> pharmaceutical<\/span> products<\/span> to<\/span> achieve<\/span> modification,<\/span> control<\/span> the<\/span> release<\/span> of<\/span> a<\/span> medicinal<\/span> substance.<\/span> All<\/span> coatings<\/span> on<\/span> the<\/span> kinetics<\/span> of<\/span> drug<\/span> release<\/span> can<\/span> be<\/span> divided<\/span> into<\/span> the<\/span> following<\/span> four<\/span> types:<\/span> Coatings<\/span> that<\/span> provide<\/span> periodic<\/span> release<\/span> of<\/span> LV<\/span> (intermittent<\/span> release).<\/span> This<\/span> type<\/span> includes<\/span> coatings<\/span> resistant<\/span> to<\/span> the<\/span> effects<\/span> of<\/span> gastric<\/span> juice<\/span> \u2014<\/span> intestinal<\/span> soluble<\/span> coatings.<\/span> Coatings<\/span> that<\/span> provide<\/span> instant<\/span> release<\/span> of<\/span> LV.<\/span> Coatings<\/span> that<\/span> provide<\/span> a<\/span> steady<\/span> (continuous)<\/span> release<\/span> of<\/span> LV.<\/span> Coatings<\/span> that<\/span> provide<\/span> delayed<\/span> (delayed)<\/span> release<\/span> of<\/span> LV.<\/span> Let's<\/span> look<\/span> at<\/span> each<\/span> type<\/span> of<\/span> coatings<\/span> in<\/span> more<\/span> detail.<\/span> Coatings<\/span> that<\/span> provide<\/span> periodic<\/span> release<\/span> of<\/span> the<\/span> medicinal<\/span> substance.<\/span> This<\/span> type<\/span> of<\/span> coating<\/span> provides<\/span> a<\/span> prolonged<\/span> effect<\/span> of<\/span> the<\/span> dosage<\/span> form,<\/span> when<\/span> injected<\/span> into<\/span> the<\/span> body,<\/span> LV<\/span> is<\/span> released<\/span> in<\/span> portions,<\/span> which<\/span> resembles<\/span> the<\/span> plasma<\/span> concentrations<\/span> created<\/span> by<\/span> the<\/span> usual<\/span> intake<\/span> for<\/span> every<\/span> 4<\/span> hours.<\/span> Such<\/span> coatings<\/span> ensure<\/span> the<\/span> repeated<\/span> effect<\/span> of<\/span> the<\/span> drug.<\/span>\nIn<\/span> dosage<\/span> forms<\/span> with<\/span> this<\/span> type<\/span> of<\/span> coatings,<\/span> one<\/span> dose<\/span> is<\/span> separated<\/span> from<\/span> the<\/span> other<\/span> by<\/span> a<\/span> barrier<\/span> layer,<\/span> which<\/span> can<\/span> be<\/span> film,<\/span> pressed<\/span> or<\/span> coated.<\/span> Depending<\/span> on<\/span> the<\/span> composition<\/span> of<\/span> the<\/span> layer,<\/span> the<\/span> dose<\/span> of<\/span> the<\/span> medicinal<\/span> substance<\/span> can<\/span> be<\/span> released<\/span> either<\/span> after<\/span> a<\/span> given<\/span> time,<\/span> regardless<\/span> of<\/span> the<\/span> localization<\/span> of<\/span> the<\/span> drug<\/span> in<\/span> the<\/span> gastrointestinal<\/span> tract,<\/span> or<\/span> at<\/span> a<\/span> certain<\/span> time<\/span> in<\/span> the<\/span> necessary<\/span> part<\/span> of<\/span> the<\/span> digestive<\/span> tract.<\/span> This<\/span> type<\/span> of<\/span> coating<\/span> includes<\/span> intestinal<\/span> soluble<\/span> coatings.<\/span> They<\/span> are<\/span> usually<\/span> insoluble<\/span> in<\/span> the<\/span> stomach,<\/span> but<\/span> easily<\/span> dissolve<\/span> when<\/span> ingested<\/span> in<\/span> the<\/span> small<\/span> intestine.<\/span>\n\n[\/vc_column_text][\/vc_column][\/vc_row]<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text] Modified release film coatings can be applied to pharmaceutical products to achieve modification, control the release of a medicinal substance. All coatings on the kinetics of drug release can be divided into the following four types: Coatings that provide periodic release of LV (intermittent release). This type includes coatings resistant to the effects of…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"two_page_speed":[]},"categories":[2185,2175],"tags":[2380,75,77,76,2381,2372,2376,2373,2378,2374,78,43,2186,2377,2370,2379,2189,2190,63,95,2375,2371,212],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Author Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"FILM-COATING OF TABLETS<\/a> PHARMACEUTICAL PRODUCTION TECHNOLOGIES<\/a>","rttpg_excerpt":"[vc_row][vc_column][vc_column_text] Modified release film coatings can be applied to pharmaceutical products to achieve modification, control the release of a medicinal substance. All coatings on the kinetics of drug release can be divided into the following four types: Coatings that provide periodic release of LV (intermittent release). This type includes coatings resistant to the effects of...","_links":{"self":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/58222"}],"collection":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/comments?post=58222"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/58222\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/media?parent=58222"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/categories?post=58222"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/tags?post=58222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}