{"id":58033,"date":"2024-01-16T12:55:10","date_gmt":"1970-01-01T00:00:00","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=58033"},"modified":"2024-02-13T10:20:17","modified_gmt":"2024-02-13T07:20:17","slug":"filling-gelatin-capsules-with-powders-and-granules","status":"publish","type":"post","link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/pharmaceutical-production-technologies\/filling-gelatin-capsules-with-powders-and-granules\/","title":{"rendered":"Filling gelatin capsules with powders and granules"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text]<\/span>\n\nThe<\/span> reproduction<\/span> and<\/span> accuracy<\/span> of<\/span> dosing<\/span> depends<\/span> on<\/span> the<\/span> characteristics<\/span> of<\/span> the<\/span> filler,<\/span> the<\/span> filling<\/span> method<\/span> and<\/span> the<\/span> type<\/span> of<\/span> filling<\/span> machine.<\/span> Active<\/span> substances<\/span> for<\/span> filling<\/span> into<\/span> solid<\/span> gelatin<\/span> capsules<\/span> must<\/span> meet<\/span> the<\/span> following<\/span> requirements:<\/span> the<\/span> contents<\/span> must<\/span> be<\/span> released<\/span> from<\/span> the<\/span> capsule,<\/span> providing<\/span> high<\/span> bioavailability;<\/span> when<\/span> using<\/span> automatic<\/span> filling<\/span> machines,<\/span> active<\/span> substances<\/span> must<\/span> have<\/span> certain<\/span> physico-chemical<\/span> and<\/span> technological<\/span> properties,<\/span> such<\/span> as:<\/span> certain<\/span> particle<\/span> size<\/span> and<\/span> shape;<\/span> the<\/span> same<\/span> particle<\/span> size;<\/span> mixing<\/span> homogeneity;<\/span> flowability<\/span> (fluidity);<\/span> moisture<\/span> content;<\/span> ability<\/span> to<\/span> form<\/span> compactly<\/span> under<\/span> pressure.<\/span> To<\/span> fill<\/span> solid<\/span> gelatin<\/span> capsules,<\/span> machines<\/span> of<\/span> various<\/span> companies<\/span> are<\/span> used,<\/span> differing<\/span> in<\/span> performance,<\/span> dosing<\/span> accuracy<\/span> and<\/span> the<\/span> structure<\/span> of<\/span> the<\/span> dispenser.<\/span>\n\n[\/vc_column_text][\/vc_column][\/vc_row]<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text] The reproduction and accuracy of dosing depends on the characteristics of the filler, the filling method and the type of filling machine. Active substances for filling into solid gelatin capsules must meet the following requirements: the contents must be released from the capsule, providing high bioavailability; when using automatic filling machines, active substances must…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"two_page_speed":[]},"categories":[2175,2177],"tags":[2380,2381,2372,2376,2373,143,88,2378,2374,87,85,86,84,141,81,2377,2370,2379,39,142,2375,82,2371,83],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Author Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"PHARMACEUTICAL PRODUCTION TECHNOLOGIES<\/a> PRODUCTION OF GELATIN CAPSULES FOR MEDICINES<\/a>","rttpg_excerpt":"[vc_row][vc_column][vc_column_text] The reproduction and accuracy of dosing depends on the characteristics of the filler, the filling method and the type of filling machine. Active substances for filling into solid gelatin capsules must meet the following requirements: the contents must be released from the capsule, providing high bioavailability; when using automatic filling machines, active substances must...","_links":{"self":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/58033"}],"collection":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/comments?post=58033"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/58033\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/media?parent=58033"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/categories?post=58033"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/tags?post=58033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}