{"id":57632,"date":"2024-01-16T11:46:20","date_gmt":"1970-01-01T00:00:00","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=57632"},"modified":"2024-01-16T11:46:20","modified_gmt":"1970-01-01T00:00:00","slug":"introduction-to-medical-capsule-production-technology","status":"publish","type":"post","link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/pharmaceutical-production-technologies\/introduction-to-medical-capsule-production-technology\/","title":{"rendered":"Introduction to medical capsule production technology"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text]<\/span>\n\nCapsule<\/span> (from<\/span> Lat.<\/span> capsula<\/span> \u2014<\/span> a<\/span> case<\/span> or<\/span> shell)<\/span> is<\/span> a<\/span> metered<\/span> dosage<\/span> form<\/span> consisting<\/span> of<\/span> a<\/span> drug<\/span> enclosed<\/span> in<\/span> a<\/span> shell.<\/span> In<\/span> 1846,<\/span> Frenchman<\/span> Jules<\/span> Leuby<\/span> received<\/span> a<\/span> patent<\/span> for<\/span> a<\/span> \"method<\/span> of<\/span> manufacturing<\/span> medicinal<\/span> coatings\".<\/span> He<\/span> was<\/span> the<\/span> first<\/span> to<\/span> start<\/span> making<\/span> two-piece<\/span> capsules,<\/span> which<\/span> he<\/span> received<\/span> by<\/span> lowering<\/span> metal<\/span> pins<\/span> fixed<\/span> on<\/span> a<\/span> disk<\/span> into<\/span> a<\/span> gelatin<\/span> solution.<\/span> The<\/span> two<\/span> parts<\/span> were<\/span> adjusted<\/span> to<\/span> each<\/span> other<\/span> and<\/span> formed<\/span> a<\/span> \"cylindrical<\/span> box<\/span> in<\/span> the<\/span> shape<\/span> of<\/span> a<\/span> silkworm<\/span> cocoon.\"<\/span> In<\/span> these<\/span> capsules,<\/span> pharmacists<\/span> could<\/span> already<\/span> put<\/span> powders<\/span> or<\/span> mixtures<\/span> thereof,<\/span> made<\/span> according<\/span> to<\/span> a<\/span> doctor's<\/span> prescription.<\/span> In<\/span> its<\/span> modern<\/span> form,<\/span> this<\/span> method<\/span> is<\/span> used<\/span> in<\/span> the<\/span> production<\/span> of<\/span> solid<\/span> bivalve<\/span> gelatin<\/span> capsules.<\/span> Capsules<\/span> in<\/span> their<\/span> modern<\/span> form<\/span> can<\/span> be<\/span> considered<\/span> a<\/span> relatively<\/span> young<\/span> dosage<\/span> form.<\/span> The<\/span> impetus<\/span> for<\/span> the<\/span> development<\/span> of<\/span> such<\/span> a<\/span> dosage<\/span> form<\/span> as<\/span> capsules<\/span> was<\/span> the<\/span> beginning<\/span> of<\/span> the<\/span> widespread<\/span> use<\/span> of<\/span> antibiotics<\/span> in<\/span> medical<\/span> practice,<\/span> characterized<\/span> by<\/span> an<\/span> unpleasant<\/span> bitter<\/span> taste.<\/span> Currently,<\/span> encapsulated<\/span> medicines<\/span> are<\/span> becoming<\/span> increasingly<\/span> important<\/span> due<\/span> to<\/span> their<\/span> obvious<\/span> advantages<\/span> over<\/span> other<\/span> medicinal<\/span> forms.<\/span>\n\n[\/vc_column_text][\/vc_column][\/vc_row]<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text] Capsule (from Lat. capsula \u2014 a case or shell) is a metered dosage form consisting of a drug enclosed in a shell. In 1846, Frenchman Jules Leuby received a patent for a “method of manufacturing medicinal coatings”. He was the first to start making two-piece capsules, which he received by lowering metal pins fixed…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"two_page_speed":[]},"categories":[2175,2177],"tags":[2380,2381,2372,2376,2373,2378,2374,86,87,85,84,141,81,2377,2370,2379,39,142,2375,82,2371,83],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Author Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/pharmaceutical-equipment\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"PHARMACEUTICAL PRODUCTION TECHNOLOGIES<\/a> PRODUCTION OF GELATIN CAPSULES FOR MEDICINES<\/a>","rttpg_excerpt":"[vc_row][vc_column][vc_column_text] Capsule (from Lat. capsula \u2014 a case or shell) is a metered dosage form consisting of a drug enclosed in a shell. In 1846, Frenchman Jules Leuby received a patent for a \"method of manufacturing medicinal coatings\". He was the first to start making two-piece capsules, which he received by lowering metal pins fixed...","_links":{"self":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/57632"}],"collection":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/comments?post=57632"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/posts\/57632\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/media?parent=57632"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/categories?post=57632"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/pharmaceutical-equipment\/wp-json\/wp\/v2\/tags?post=57632"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}