{"id":67514,"date":"2024-01-16T12:22:20","date_gmt":"2024-01-16T09:22:20","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=67514"},"modified":"2024-04-02T12:32:31","modified_gmt":"2024-04-02T09:32:31","slug":"recubrimientos-de-grageas-en-tabletas-grageas-capsulas-nueces-chicles","status":"publish","type":"post","link":"https:\/\/minipress.ru\/farmaceutico-equipos\/fabricacion-de-medicamentos-de-expertos\/recubrimientos-de-grageas-en-tabletas-grageas-capsulas-nueces-chicles\/","title":{"rendered":"RECUBRIMIENTOS DE GRAGEAS EN TABLETAS, GRAGEAS, C\u00c1PSULAS, NUECES, CHICLES"},"content":{"rendered":"
El<\/span> t\u00e9rmino<\/span> \"<\/span> recubrimiento<\/span> recubierto<\/span> \"proviene<\/span> de<\/span> la<\/span> palabra<\/span> francesa\"<\/span> gragea<\/span> \"y<\/span> significa\"<\/span> aplicar<\/span> un<\/span> recubrimiento<\/span> de<\/span> az\u00facar\".<\/span>\r\n\r\nUna<\/span> tableta<\/span> drenada<\/span> consiste<\/span> en<\/span> una<\/span> tableta<\/span> central<\/span> que<\/span> contiene<\/span> una<\/span> sustancia<\/span> medicinal<\/span> (sustancia)<\/span> y<\/span> un<\/span> recubrimiento<\/span> que<\/span> contiene<\/span> varios<\/span> excipientes.<\/span> La<\/span> tableta<\/span> central<\/span> debe<\/span> ser<\/span> mec\u00e1nicamente<\/span> fuerte.<\/span> Las<\/span> tabletas<\/span> que<\/span> se<\/span> van<\/span> a<\/span> drenar<\/span> no<\/span> deben<\/span> tener<\/span> una<\/span> forma<\/span> plana<\/span> para<\/span> evitar<\/span> que<\/span> se<\/span> peguen<\/span> entre<\/span> s\u00ed.<\/span>\r\n\r\nConsideremos<\/span> uno<\/span> de<\/span> los<\/span> viejos<\/span> m\u00e9todos<\/span> de<\/span> recubrimiento:<\/span> recubrimiento<\/span> de<\/span> az\u00facar.<\/span> El<\/span> recubrimiento<\/span> de<\/span> az\u00facar<\/span> es<\/span> una<\/span> forma<\/span> efectiva<\/span> de<\/span> aplicar<\/span> grandes<\/span> capas<\/span> de<\/span> recubrimientos,<\/span> principalmente<\/span> para<\/span> enmascarar<\/span> el<\/span> sabor.<\/span> Este<\/span> tipo<\/span> de<\/span> recubrimiento<\/span> se<\/span> usa<\/span> para<\/span> formas<\/span> farmac\u00e9uticas<\/span> s\u00f3lidas<\/span> sensibles<\/span> a<\/span> la<\/span> temperatura<\/span> y<\/span> quebradizas.<\/span>\r\n\r\nLa<\/span> primera<\/span> etapa<\/span> de<\/span> esta<\/span> tecnolog\u00eda<\/span> es<\/span> la<\/span> pulverizaci\u00f3n<\/span> de<\/span> una<\/span> soluci\u00f3n<\/span> para<\/span> pulverizar<\/span> sobre<\/span> una<\/span> part\u00edcula(tableta,<\/span> gr\u00e1nulo).<\/span> El<\/span> aire<\/span> suministrado<\/span> al<\/span> dispositivo<\/span> evapora<\/span> el<\/span> l\u00edquido<\/span> y<\/span> seca<\/span> la<\/span> capa<\/span> de<\/span> az\u00facar.<\/span> Con<\/span> el<\/span> suministro<\/span> intermitente<\/span> de<\/span> la<\/span> soluci\u00f3n,<\/span> las<\/span> part\u00edculas<\/span> permanecen<\/span> en<\/span> el<\/span> proceso<\/span> hasta<\/span> que<\/span> se<\/span> alcanza<\/span> el<\/span> espesor<\/span> de<\/span> capa<\/span> deseado.<\/span> El<\/span> recubrimiento<\/span> de<\/span> part\u00edculas<\/span> se<\/span> lleva<\/span> a<\/span> cabo<\/span> de<\/span> manera<\/span> uniforme<\/span> sobre<\/span> la<\/span> superficie,<\/span> mientras<\/span> que<\/span> la<\/span> masa<\/span> de<\/span> la<\/span> capa<\/span> var\u00eda<\/span> de<\/span> 0,5<\/span> a<\/span> 2<\/span> mm.<\/span> Actualmente,<\/span> se<\/span> est\u00e1n<\/span> drenando<\/span> una<\/span> gran<\/span> cantidad<\/span> de<\/span> tabletas,<\/span> que<\/span> incluyen:<\/span> tabletas<\/span> de<\/span> algunos<\/span> medicamentos<\/span> hormonales;<\/span> algunos<\/span> agentes<\/span> coler\u00e9ticos;<\/span> preparaciones<\/span> sint\u00e9ticas<\/span> (\u00e1cido<\/span> glut\u00e1mico,<\/span> akrikhin,<\/span> diprozina,<\/span> metionina,<\/span> etc.);<\/span> una<\/span> serie<\/span> de<\/span> extractos<\/span> (espino<\/span> cerval,<\/span> krovohlebki,<\/span> krasavki,<\/span> etc.)<\/span>\r\n\r\nEl<\/span> drenaje<\/span> se<\/span> realiza<\/span> en<\/span> m\u00e1quina<\/span> de<\/span> drenaje<\/span> (obductores)<\/span> de<\/span> tres<\/span> formas:<\/span> esf\u00e9rica,<\/span> elipsoide<\/span> y<\/span> en<\/span> forma<\/span> de<\/span> pera.<\/span> La<\/span> m\u00e1s<\/span> com\u00fan<\/span> es<\/span> una<\/span> forma<\/span> elipsoide.<\/span> Sus<\/span> ventajas<\/span> consisten<\/span> en<\/span> la<\/span> posibilidad<\/span> de<\/span> una<\/span> mayor<\/span> carga<\/span> de<\/span> comprimidos,<\/span> logrando<\/span> as\u00ed<\/span> una<\/span> mayor<\/span> productividad<\/span> durante<\/span> este<\/span> proceso.<\/span> Adem\u00e1s,<\/span> la<\/span> m\u00e1quina<\/span> de<\/span> recubrimiento<\/span> elipsoidal<\/span> crea<\/span> movimientos<\/span> de<\/span> rotaci\u00f3n<\/span> \u00f3ptimos<\/span> de<\/span> los<\/span> comprimidos<\/span> recubiertos,<\/span> acelerando<\/span> y<\/span> mejorando<\/span> las<\/span> condiciones<\/span> de<\/span> recubrimiento.<\/span>\r\n\r\nLa<\/span> m\u00e1quina<\/span> de<\/span> recubrimiento<\/span> gira<\/span> en<\/span> el<\/span> sentido<\/span> de<\/span> las<\/span> agujas<\/span> del<\/span> reloj<\/span> alrededor<\/span> del<\/span> eje,<\/span> ubicado<\/span> en<\/span> un<\/span> \u00e1ngulo<\/span> (mezcla<\/span> vertical<\/span> y<\/span> horizontal),<\/span> lo<\/span> que<\/span> le<\/span> permite<\/span> lograr<\/span> una<\/span> buena<\/span> mezcla.<\/span> El<\/span> di\u00e1metro<\/span> de<\/span> la<\/span> m\u00e1quina<\/span> de<\/span> recubrimiento,<\/span> la<\/span> mayor\u00eda<\/span> de<\/span> las<\/span> veces<\/span> hecha<\/span> de<\/span> cobre,<\/span> var\u00eda<\/span> de<\/span> 0,7<\/span> a<\/span> 1,5<\/span> m.<\/span> El<\/span> \u00e1ngulo<\/span> de<\/span> inclinaci\u00f3n<\/span> de<\/span> la<\/span> m\u00e1quina<\/span> de<\/span> recubrimiento<\/span> con<\/span> respecto<\/span> a<\/span> la<\/span> horizontal<\/span> es<\/span> de<\/span> 30<\/span> \u00b0<\/span> -45\u00b0,<\/span> la<\/span> carga<\/span> \u00f3ptima<\/span> es<\/span> del<\/span> 25-30%<\/span> del<\/span> volumen<\/span> de<\/span> recubrimiento.<\/span> La<\/span> velocidad<\/span> de<\/span> rotaci\u00f3n<\/span> \u00f3ptima<\/span> de<\/span> la<\/span> m\u00e1quina<\/span> de<\/span> recubrimiento<\/span> es<\/span> de<\/span> 20-40<\/span> rpm,<\/span> el<\/span> n\u00famero<\/span> de<\/span> revoluciones<\/span> se<\/span> selecciona<\/span> seg\u00fan<\/span> el<\/span> curso<\/span> del<\/span> proceso<\/span> tecnol\u00f3gico.<\/span>\r\n\r\nCualquiera<\/span> que<\/span> sea<\/span> la<\/span> tarea<\/span> que<\/span> tenga<\/span> por<\/span> delante,<\/span> MINIPRESS<\/span> est\u00e1<\/span> lista<\/span> para<\/span> asumirla.<\/span> Somos<\/span> m\u00e1s<\/span> poderosos<\/span> que<\/span> muchos<\/span> competidores<\/span> y<\/span> nuestro<\/span> servicio<\/span> es<\/span> mucho<\/span> m\u00e1s<\/span> conveniente.<\/span> Brindamos<\/span> a<\/span> nuestros<\/span> clientes<\/span> condiciones<\/span> impresionantes<\/span> y<\/span> ejecutamos<\/span> \u00f3rdenes<\/span> incre\u00edblemente<\/span> r\u00e1pido.<\/span> Nuestros<\/span> especialistas<\/span> utilizan<\/span> las<\/span> tecnolog\u00edas<\/span> m\u00e1s<\/span> avanzadas<\/span> del<\/span> mundo<\/span> para<\/span> seleccionar<\/span> diversos<\/span> equipos.<\/span> Tenemos<\/span> todo<\/span> lo<\/span> que<\/span> necesita<\/span> para<\/span> una<\/span> producci\u00f3n<\/span> moderna<\/span> a<\/span> cualquier<\/span> nivel.<\/span> Y<\/span> a\u00fan<\/span> m\u00e1s.<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
El t\u00e9rmino \u00bb recubrimiento recubierto \u00abproviene de la palabra francesa\u00bb gragea \u00aby significa\u00bb aplicar un recubrimiento de az\u00facar\u00bb. Una tableta drenada consiste en una tableta central que contiene una sustancia medicinal (sustancia) y un recubrimiento que contiene varios excipientes. La tableta central debe ser mec\u00e1nicamente fuerte. Las tabletas que se van a drenar no deben…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"footnotes":""},"categories":[3010,2299],"tags":[2380,2381,81,43,2373,75,41,78,2377,2370,76,63,2372,2379,95,2376,2375,2371],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Autor Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/farmaceutico-equipos\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"EMBALAJE DE TABLETAS<\/a> FABRICACI\u00d3N DE MEDICAMENTOS DE EXPERTOS<\/a>","rttpg_excerpt":"El t\u00e9rmino \" recubrimiento recubierto \"proviene de la palabra francesa\" gragea \"y significa\" aplicar un recubrimiento de az\u00facar\". Una tableta drenada consiste en una tableta central que contiene una sustancia medicinal (sustancia) y un recubrimiento que contiene varios excipientes. La tableta central debe ser mec\u00e1nicamente fuerte. Las tabletas que se van a drenar no deben...","_links":{"self":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/67514"}],"collection":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/comments?post=67514"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/67514\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/media?parent=67514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/categories?post=67514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/tags?post=67514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}