{"id":59835,"date":"2024-01-16T13:20:35","date_gmt":"1970-01-01T00:00:00","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=59835"},"modified":"2024-03-22T17:11:20","modified_gmt":"2024-03-22T14:11:20","slug":"operaciones-de-produccion-de-polvo-y-equipos-utilizados","status":"publish","type":"post","link":"https:\/\/minipress.ru\/farmaceutico-equipos\/tecnologias-y-equipos-para-la-produccion-de-polvos\/operaciones-de-produccion-de-polvo-y-equipos-utilizados\/","title":{"rendered":"Operaciones de producci\u00f3n de polvo y equipos utilizados"},"content":{"rendered":"
The<\/span> technological<\/span> scheme<\/span> of<\/span> powder<\/span> production<\/span> includes<\/span> the<\/span> following<\/span> operations:<\/span> grinding,<\/span> sieving,<\/span> mixing<\/span> (in<\/span> the<\/span> manufacture<\/span> of<\/span> complex<\/span> powders),<\/span> dosing<\/span> (packing)<\/span> and<\/span> packaging.<\/span> The<\/span> need<\/span> to<\/span> perform<\/span> certain<\/span> technological<\/span> operations<\/span> depends<\/span> on<\/span> the<\/span> prescription,<\/span> medical<\/span> purpose<\/span> and<\/span> type<\/span> of<\/span> starting<\/span> preparations.<\/span> If<\/span> the<\/span> starting<\/span> materials<\/span> (medicinal<\/span> and<\/span> auxiliary<\/span> substances)<\/span> do<\/span> not<\/span> meet<\/span> the<\/span> required<\/span> fractional<\/span> composition<\/span> specified<\/span> in<\/span> the<\/span> regulations,<\/span> they<\/span> are<\/span> crushed.<\/span> Grinding<\/span> refers<\/span> to<\/span> the<\/span> mechanical<\/span> process<\/span> of<\/span> dividing<\/span> pieces<\/span> of<\/span> solids<\/span> into<\/span> smaller<\/span> ones<\/span> or<\/span> turning<\/span> them<\/span> into<\/span> powder,<\/span> as<\/span> a<\/span> result<\/span> of<\/span> which<\/span> the<\/span> surface<\/span> of<\/span> the<\/span> processed<\/span> material<\/span> increases<\/span> significantly,<\/span> which<\/span> significantly<\/span> accelerates<\/span> the<\/span> dissolution<\/span> of<\/span> medicinal<\/span> substances.<\/span> The<\/span> goals<\/span> of<\/span> grinding<\/span> are<\/span> as<\/span> follows:<\/span> to<\/span> provide<\/span> a<\/span> rapid<\/span> therapeutic<\/span> effect<\/span> by<\/span> reducing<\/span> the<\/span> particle<\/span> size<\/span> and<\/span> increasing<\/span> the<\/span> amount<\/span> of<\/span> substance;<\/span> to<\/span> obtain<\/span> a<\/span> uniform<\/span> powder<\/span> mixture;<\/span> to<\/span> ensure<\/span> the<\/span> accuracy<\/span> of<\/span> dosing<\/span> when<\/span> dividing<\/span> the<\/span> powder<\/span> mass<\/span> into<\/span> separate<\/span> doses;<\/span> to<\/span> obtain<\/span> a<\/span> semi-finished<\/span> product<\/span> used<\/span> by<\/span> the<\/span> enterprise<\/span> for<\/span> the<\/span> manufacture<\/span> of<\/span> solutions,<\/span> extracts,<\/span> tablets.<\/span> The<\/span> main<\/span> goal<\/span> of<\/span> the<\/span> grinding<\/span> stage<\/span> is<\/span> to<\/span> achieve<\/span> a<\/span> faster<\/span> and<\/span> more<\/span> complete<\/span> therapeutic<\/span> effect<\/span> by<\/span> reducing<\/span> the<\/span> particle<\/span> size<\/span> and<\/span> increasing<\/span> their<\/span> number.<\/span> Grinding<\/span> is<\/span> necessary<\/span> not<\/span> only<\/span> to<\/span> achieve<\/span> a<\/span> greater<\/span> therapeutic<\/span> effect,<\/span> but<\/span> also<\/span> for<\/span> more<\/span> accurate<\/span> dosing:<\/span> when<\/span> grinding,<\/span> the<\/span> particle<\/span> size<\/span> of<\/span> medicinal<\/span> substances<\/span> is<\/span> leveled,<\/span> after<\/span> which<\/span> they<\/span> mix<\/span> well<\/span> and<\/span> do<\/span> not<\/span> delaminate<\/span> during<\/span> dosing.<\/span> It<\/span> is<\/span> known<\/span> that<\/span> with<\/span> a<\/span> decrease<\/span> in<\/span> the<\/span> particle<\/span> size,<\/span> the<\/span> surface<\/span> energy<\/span> of<\/span> the<\/span> crushed<\/span> medicinal<\/span> substance<\/span> increases<\/span> sharply.<\/span> With<\/span> fine<\/span> grinding,<\/span> LV<\/span> dissolves<\/span> better,<\/span> participates<\/span> faster<\/span> and<\/span> more<\/span> fully<\/span> in<\/span> chemical<\/span> reactions.<\/span> Grinding<\/span> can<\/span> significantly<\/span> affect<\/span> the<\/span> therapeutic<\/span> activity<\/span> of<\/span> LV<\/span> due<\/span> to<\/span> changes<\/span> in<\/span> their<\/span> absorption<\/span> processes.<\/span> This<\/span> happens<\/span> when<\/span> the<\/span> solubility<\/span> of<\/span> LV<\/span> changes,<\/span> the<\/span> rate<\/span> of<\/span> which<\/span> is<\/span> directly<\/span> proportional<\/span> to<\/span> the<\/span> surface<\/span> area<\/span> and<\/span> inversely<\/span> proportional<\/span> to<\/span> the<\/span> size<\/span> of<\/span> the<\/span> particles<\/span> of<\/span> the<\/span> substance,<\/span> i.e.<\/span> the<\/span> rate<\/span> and<\/span> completeness<\/span> of<\/span> absorption<\/span> of<\/span> the<\/span> medicinal<\/span> substance,<\/span> its<\/span> concentration<\/span> and<\/span> residence<\/span> time<\/span> in<\/span> the<\/span> body<\/span> largely<\/span> depend<\/span> on<\/span> the<\/span> particle<\/span> size.<\/span>\r\n<\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
The technological scheme of powder production includes the following operations: grinding, sieving, mixing (in the manufacture of complex powders), dosing (packing) and packaging. The need to perform certain technological operations depends on the prescription, medical purpose and type of starting preparations. If the starting materials (medicinal and auxiliary substances) do not meet the required fractional…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"footnotes":""},"categories":[3689,2243],"tags":[2380,2381,263,43,2378,2374,2373,120,2262,2377,2370,2230,227,220,226,2372,2379,2376,119,2375,2371,116],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Autor Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/farmaceutico-equipos\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"PRECIO DE M\u00c1QUINAS DE ENVASADO HORIZONTAL<\/a> TECNOLOG\u00cdAS Y EQUIPOS PARA LA PRODUCCI\u00d3N DE POLVOS<\/a>","rttpg_excerpt":"The technological scheme of powder production includes the following operations: grinding, sieving, mixing (in the manufacture of complex powders), dosing (packing) and packaging. The need to perform certain technological operations depends on the prescription, medical purpose and type of starting preparations. If the starting materials (medicinal and auxiliary substances) do not meet the required fractional...","_links":{"self":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/59835"}],"collection":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/comments?post=59835"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/59835\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/media?parent=59835"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/categories?post=59835"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/tags?post=59835"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}