{"id":59562,"date":"2024-01-16T13:36:03","date_gmt":"2024-01-16T10:36:03","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=59562"},"modified":"2024-03-29T14:55:06","modified_gmt":"2024-03-29T11:55:06","slug":"granulacion-en-seco-de-polvos","status":"publish","type":"post","link":"https:\/\/minipress.ru\/farmaceutico-equipos\/tecnologias-de-produccion-farmaceutica\/granulacion-en-seco-de-polvos\/","title":{"rendered":"Granulaci\u00f3n en seco de polvos"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text]<\/span>\r\n\r\nDry<\/span> granulation<\/span> is<\/span> a<\/span> method<\/span> in<\/span> which<\/span> a<\/span> powdery<\/span> material<\/span> (a<\/span> mixture<\/span> of<\/span> medicinal<\/span> and<\/span> auxiliary<\/span> substances)<\/span> is<\/span> compacted<\/span> to<\/span> produce<\/span> a<\/span> granulate.<\/span> Dry<\/span> granulation<\/span> is<\/span> used<\/span> in<\/span> cases<\/span> where<\/span> wet<\/span> granulation<\/span> affects<\/span> the<\/span> stability<\/span> and\/or<\/span> physico-chemical<\/span> characteristics<\/span> of<\/span> the<\/span> medicinal<\/span> substance,<\/span> as<\/span> well<\/span> as<\/span> when<\/span> the<\/span> medicinal<\/span> and<\/span> auxiliary<\/span> substances<\/span> are<\/span> poorly<\/span> compressed<\/span> after<\/span> the<\/span> wet<\/span> granulation<\/span> process.<\/span>\r\nIf<\/span> medicinal<\/span> substances<\/span> undergo<\/span> physical<\/span> changes<\/span> during<\/span> drying<\/span> (melting,<\/span> softening,<\/span> color<\/span> change)<\/span> or<\/span> enter<\/span> into<\/span> chemical<\/span> reactions,<\/span> they<\/span> are<\/span> briquetted,<\/span> i.e.<\/span> briquettes<\/span> are<\/span> pressed<\/span> from<\/span> the<\/span> powder<\/span> on<\/span> special<\/span> briquetting<\/span> presses<\/span> with<\/span> large<\/span> matrices<\/span> (25x25<\/span> mm)<\/span> under<\/span> high<\/span> pressure.<\/span>\r\n\r\n[\/vc_column_text][\/vc_column][\/vc_row]<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text] Dry granulation is a method in which a powdery material (a mixture of medicinal and auxiliary substances) is compacted to produce a granulate. Dry granulation is used in cases where wet granulation affects the stability and\/or physico-chemical characteristics of the medicinal substance, as well as when the medicinal and auxiliary substances are poorly compressed…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"footnotes":""},"categories":[2232,2175],"tags":[2380,2381,43,2378,2374,2373,39,2239,67,72,65,68,64,2377,2370,71,2372,2379,2189,2376,2375,2371,2240,2192],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Autor Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/farmaceutico-equipos\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"PROCESO DE GRANULACI\u00d3N EN LA PRODUCCI\u00d3N DE COMPRIMIDOS<\/a> TECNOLOG\u00cdAS DE PRODUCCI\u00d3N FARMAC\u00c9UTICA<\/a>","rttpg_excerpt":"[vc_row][vc_column][vc_column_text] Dry granulation is a method in which a powdery material (a mixture of medicinal and auxiliary substances) is compacted to produce a granulate. Dry granulation is used in cases where wet granulation affects the stability and\/or physico-chemical characteristics of the medicinal substance, as well as when the medicinal and auxiliary substances are poorly compressed...","_links":{"self":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/59562"}],"collection":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/comments?post=59562"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/59562\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/media?parent=59562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/categories?post=59562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/tags?post=59562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}