{"id":59558,"date":"2024-01-16T13:36:03","date_gmt":"2024-01-16T10:36:03","guid":{"rendered":"https:\/\/minipress.ru\/katalog\/?p=59558"},"modified":"2024-03-29T14:54:48","modified_gmt":"2024-03-29T11:54:48","slug":"aglutinantes-para-granulacion-humeda","status":"publish","type":"post","link":"https:\/\/minipress.ru\/farmaceutico-equipos\/tecnologias-de-produccion-farmaceutica\/aglutinantes-para-granulacion-humeda\/","title":{"rendered":"Aglutinantes para granulaci\u00f3n h\u00fameda"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text]<\/span>\r\n\r\nThere<\/span> are<\/span> some<\/span> requirements<\/span> for<\/span> the<\/span> granulating<\/span> liquid,<\/span> one<\/span> of<\/span> them<\/span> is<\/span> that<\/span> the<\/span> granulating<\/span> liquid<\/span> should<\/span> not<\/span> dissolve<\/span> the<\/span> active<\/span> substance.<\/span> Water,<\/span> an<\/span> aqueous<\/span> solution<\/span> of<\/span> ethanol,<\/span> acetone<\/span> and<\/span> methylene<\/span> chloride<\/span> can<\/span> be<\/span> used<\/span> as<\/span> a<\/span> granulating<\/span> liquid.<\/span> A<\/span> wide<\/span> range<\/span> of<\/span> substances<\/span> are<\/span> used<\/span> as<\/span> binding<\/span> agents<\/span> for<\/span> wet<\/span> granulation<\/span> in<\/span> modern<\/span> pharmaceutical<\/span> production,<\/span> for<\/span> example:<\/span> starch<\/span> (5-15%<\/span> g\/g),<\/span> starch<\/span> derivatives,<\/span> cellulose<\/span> derivatives<\/span> that<\/span> improve<\/span> the<\/span> plasticity<\/span> of<\/span> granules,<\/span> as<\/span> well<\/span> as<\/span> gelatin<\/span> (1-3%<\/span> g\/<\/span> g)<\/span> and<\/span> PVP<\/span> (3-10%<\/span> g\/<\/span> g).<\/span> The<\/span> most<\/span> common<\/span> and<\/span> effective<\/span> binder<\/span> for<\/span> wet<\/span> granulation<\/span> in<\/span> the<\/span> modern<\/span> pharmaceutical<\/span> industry<\/span> is<\/span> a<\/span> synthetic<\/span> polymer<\/span> such<\/span> as<\/span> Collidone<\/span> (PVP),<\/span> various<\/span> brands<\/span> of<\/span> which<\/span> (Collidone<\/span> 25,<\/span> 30<\/span> and<\/span> 90F)<\/span> are<\/span> widely<\/span> represented<\/span> on<\/span> the<\/span> market.<\/span>\r\n\r\n[\/vc_column_text][\/vc_column][\/vc_row]<\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text] There are some requirements for the granulating liquid, one of them is that the granulating liquid should not dissolve the active substance. Water, an aqueous solution of ethanol, acetone and methylene chloride can be used as a granulating liquid. A wide range of substances are used as binding agents for wet granulation in modern…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"inline_featured_image":false,"footnotes":""},"categories":[2232,2175],"tags":[2380,2381,43,2378,2374,2373,39,2239,67,72,65,68,64,2377,2370,71,2372,2379,2189,2376,2375,2371,2240,2192],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":".. Autor Roman Tsibulsky","author_link":"https:\/\/minipress.ru\/farmaceutico-equipos\/author\/admin\/"},"rttpg_comment":0,"rttpg_category":"PROCESO DE GRANULACI\u00d3N EN LA PRODUCCI\u00d3N DE COMPRIMIDOS<\/a> TECNOLOG\u00cdAS DE PRODUCCI\u00d3N FARMAC\u00c9UTICA<\/a>","rttpg_excerpt":"[vc_row][vc_column][vc_column_text] There are some requirements for the granulating liquid, one of them is that the granulating liquid should not dissolve the active substance. Water, an aqueous solution of ethanol, acetone and methylene chloride can be used as a granulating liquid. A wide range of substances are used as binding agents for wet granulation in modern...","_links":{"self":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/59558"}],"collection":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/comments?post=59558"}],"version-history":[{"count":0,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/posts\/59558\/revisions"}],"wp:attachment":[{"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/media?parent=59558"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/categories?post=59558"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/minipress.ru\/farmaceutico-equipos\/wp-json\/wp\/v2\/tags?post=59558"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}